Results 61 to 70 of about 5,145 (265)

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source

A Sliding Mode-Multimodel Control with Sliding Mode Observer for a Sensorless Pumping System

CoRR, 2013
This work deals with the design of a sliding mode observer with a multi-surfaces sliding mode multimodel control (SM-MMC) for a mechanical sensorless pumping system. The observer is designed to estimate the speed and the mechanical position of the DC motor operating in the process.
Rhif, Ahmed, Kardous, Zohra, Braiek, Naceur Ben Hadj   +2 more
openaire   +4 more sources

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

Sliding-Mode Observer for Speed and Position Sensorless Control of Linear-PMSM

Electrical, Control and Communication Engineering, 2014
The paper presents a sliding-mode observer that utilizes sigmoid function for speed and position sensorless control of permanent-magnet linear synchronous motor (PMLSM). In conventional sliding mode observer method there are the chattering phenomenon and
Kazraji Saeed Masoumi, Soflayi Ramin Bavili, Sharifian Mohammad Bagher Bannae   +2 more
doaj   +1 more source

Adaptive Backstepping Sliding Mode Control of the Hybrid Conveying Mechanism with Mismatched Disturbances via Nonlinear Disturbance Observers

Journal of Control Science and Engineering, 2020
An adaptive backstepping sliding mode controller combined with a nonlinear disturbance observer is designed for trajectory tracking of the electrically driven hybrid conveying mechanism with mismatched disturbances.
Wei Yuan, Guoqin Gao, Jianzhen Li
doaj   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

Implementation of Sliding Mode Observer Based Reconfiguration in an Autonomous Underwater Vehicle

Acta Polytechnica, 2005
This paper looks at the implementation of a Sliding Mode Observer (SMO) based Reconfiguration algorithm to deal with sensor faults within the context of navigation controllers for Autonomous Underwater Vehicle (AUV).
A. J. Mitchell, E. W. McGookin, D. J. Murray-Smith   +2 more
doaj  

Sensorless Fault-Tolerant Control Strategy of Six-Phase Induction Machine Based on Harmonic Suppression and Sliding Mode Observer

IEEE Access, 2019
This paper deduces a unified mathematical model of open-circuit fault of six-phase induction machine, and purposes a fault-tolerence sensorless strategy based on the sliding mode observer(SMO) to estimate the rotor flux and rotor speed.
Yiwen Geng, Zou Lai, Yonggang Li, Ding Wang, Ruicheng Chen, Pengfei Zheng   +5 more
doaj   +1 more source

Sudden anaerobization in Amphibacillus xylanus increases intracellular labile ferrous iron and inhibits cell growth

FEBS Open Bio, EarlyView.
Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata, Yoichi Sakai, Keisuke Tanaka, Etsuro Yoshimura, Ken Kitano, Morio Ishikawa, Tadahiro Nakamoto, Tsutomu Takayama, Hirofumi Inoue, Kaho Nomura, Tomonori Suzuki, Masataka Uchino, Akira Abe, Youichi Niimura   +13 more
wiley   +1 more source

Observer–Based Sliding–Mode Fault–Tolerant Consistent Control for Hybrid Event–Triggered Multi–Agent Systems

International Journal of Applied Mathematics and Computer Science
An observer-based hybrid event-triggered sliding mode fault-tolerant consistent control strategy is proposed for actuator faults in nonlinear second-order leader–follower multi-agent systems.
Xia Dexian, Fu Xingjian
doaj   +1 more source