Results 71 to 80 of about 5,377 (266)

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

Implementation of Sliding Mode Observer Based Reconfiguration in an Autonomous Underwater Vehicle

Acta Polytechnica, 2005
This paper looks at the implementation of a Sliding Mode Observer (SMO) based Reconfiguration algorithm to deal with sensor faults within the context of navigation controllers for Autonomous Underwater Vehicle (AUV).
A. J. Mitchell, E. W. McGookin, D. J. Murray-Smith   +2 more
doaj  

Design of a Sensorless Control System for LFSPM Based on Non-singular Fast Terminal Sliding Mode

Advances in Electrical and Computer Engineering
In order to achieve speed sensorless control and enhance observation accuracy for a Linear Flux-Switching Permanent Magnet (LFSPM) motor in rail transit applications, a sensorless control system is proposed in this paper, utilizing a non-singular fast ...
CHANG, Y., LI, J., ZHU, Y., LI, Y., CHEN, J.   +4 more
doaj   +1 more source

Sliding Mode and Neural Network Control of Sensorless PMSM Controlled System for Power Consumption and Performance Improvement

Energies, 2017
This paper deals with the design of sliding mode control and neural network compensation for a sensorless permanent magnet synchronous motor (PMSM) controlled system that is able to improve both power consumption and speed response performance.
Ming-Shyan Wang, Tse-Ming Tsai
doaj   +1 more source

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

FEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill, Hassan Yousef Othman AlMuallim, Elouisa Maddock, Carl Hobbs, Earl Clarke, Maria B. Goncalves, Jonathan P. T. Corcoran   +6 more
wiley   +1 more source

Effect of terahertz irradiation on DNA damage repair in living cells

FEBS Open Bio, EarlyView.
We investigated the effect of terahertz (THz) wave irradiation on DNA double‐strand break (DSB) repair in living cells. We found that THz irradiation enhanced DSB repair at specific frequencies, whereas heat treatment inhibited it, indicating that this effect is nonthermal and frequency‐specific.
Yuya Ueno, Shota Yamazaki, Hiromichi Hoshina, Masahiko Harata   +3 more
wiley   +1 more source

A Sliding Mode-Multimodel Control with Sliding Mode Observer for a Sensorless Pumping System

CoRR, 2013
This work deals with the design of a sliding mode observer with a multi-surfaces sliding mode multimodel control (SM-MMC) for a mechanical sensorless pumping system. The observer is designed to estimate the speed and the mechanical position of the DC motor operating in the process.
Rhif, Ahmed, Kardous, Zohra, Braiek, Naceur Ben Hadj   +2 more
openaire   +3 more sources

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

FEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana, Avigail Yariv, Tal Oppenheim, Hadar Amartely, Dana Reichmann, Oded Livnah   +5 more
wiley   +1 more source

Sliding Mode Flux Observer of Induction Motor

Advances in Electrical and Electronic Engineering, 2008
This paper deals with the sliding mode theory for direct torque and flux controlled (DTFC) induction motor drive. The aim of this paper is implementation of sliding mode theory for design of robust sensorless control of the drive with DTFC. This contribution describes proposed control and flux observer as well as presents simulation results and ...
Sutnar, Zdeněk, Rodič, Miran, Peroutka, Zdeněk   +2 more
openaire   +2 more sources

Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy

FEBS Open Bio, EarlyView.
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan, Ikram A. Burney, Shika Hanif Malgundkar, Siva Ramamoorthy, Ressin Varghese, Mohamed A. Al‐Kindi, Hamad Al Riyami, Shadia Al Bahlani, Sergey Dobretsov, Syed Imran Hassan, Benjamin K. Tsang, Yahya Tamimi   +11 more
wiley   +1 more source