Results 71 to 80 of about 119,331 (356)

Disturbance Observer-Based Discrete Sliding-Mode Control for a Marine Diesel Engine with Variable Sampling Control Technique

Journal of Control Science and Engineering, 2020
This paper proposes a disturbance observer-based discrete sliding-mode control scheme with the variable sampling rate control for the marine diesel engine speed control in the presence of system uncertainties and disturbances.
Xuemin Li, Yufei Liu, Haoyu Shu, Runzhi Wang, Yunlong Yang, Chunyue Feng   +5 more
doaj   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

A Battery State of Charge Estimation Method using Sliding Mode Observer

, 2008
In this paper, a simplified battery model and a closed-loop estimation method of the State of Charge (SOC) are proposed. The simplified battery model consists only of two resistors and two capacitors, based on which a sliding mode observer is designed to
Fang LJ(房立金), Lijin Fang, Guangjun Liu, Zhang F(张飞), Liu GJ(刘光军), Fei Zhang   +5 more
core   +1 more source

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

Molecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute, Madeleine Birgersson, Paolo Ceriani, Margareta Wilhelm, Ourania N Kostopoulou   +4 more
wiley   +1 more source

Disturbance attenuation–based sliding mode control with disturbance observer for mismatched uncertain system

Advances in Mechanical Engineering, 2017
A disturbance attenuation–based sliding mode control approach with an extended disturbance observer is proposed for systems with mismatched uncertainties. A novel adaptive sliding surface consisting of the disturbance estimation is presented to eliminate
Jianguo Guo, Yuchao Liu, Cheng Cheng, Jun Zhou   +3 more
doaj   +1 more source

A nonlinear observer-based sliding-mode control for piezoelectric actuator systems: theory and experiments

, 2011
This paper presents a nonlinear observer‐based sliding‐mode control for piezoelectric actuator systems (PASs). Because not all of the states of the PAS are available, an observer is required to estimate the state.
黃志良
core   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Fast Finite-Time Super-Twisting Sliding Mode Control with an Extended State Higher-Order Sliding Mode Observer for UUV Trajectory Tracking

Drones
This paper proposes a trajectory tracking control scheme consisting of a fast finite-time super-twisting sliding mode control (FSTSMC) approach and an extended state higher-order sliding mode observer (ESHSMO) for unmanned underwater vehicles (UUVs) with
Liwei Guo, Weidong Liu, Le Li, Jingming Xu, Kang Zhang, Yuang Zhang   +5 more
doaj   +1 more source

Adaptive observer-based non-linear stochastic system control with sliding mode schemes

, 2008
In this paper, an adaptive sliding mode observer is designed to reconstruct the states of non-linear stochastic systems with uncertainties from the measurable system output and the reconstructed states are employed to construct a sliding mode controller ...
Zhang, F., Qiao, F., Zhu, Quanmin, Liu, J.   +3 more
core   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source