Results 51 to 60 of about 5,377 (266)
Accelerated Adaptive Second Order Super-Twisting Sliding Mode Observer
IEEE Access, 2019 An accelerated second-order super-twisting sliding mode observer with an adaptive gain is proposed for a typical nonlinear system. The key contribution of this algorithm is that the rate of convergence of observation error is accelerated remarkably by ...
Cheng Lin +3 more
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Robust Super-Twisting Sliding Control of PAM- actuated Manipulator Based on Perturbation Observer
Cogent Engineering, 2020 This paper addresses the tracking control problem of a single-arm manipulator actuated by Pneumatic Artificial Muscle (PAM) subjected to perturbation in parameters.
Alaq Falah +3 more
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Spatial biology in cancer epigenetics
Molecular Oncology, EarlyView.Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
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Molecular Oncology, EarlyView.We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee +3 more
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Algerian Journal of Signals and SystemsThis paper proposes a multivariable sliding mode control (MSMC) based in rotor flux estimation and observer methods for squirrel cage induction motor (SCIM).
Fawzi SENANI +2 more
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Sliding mode control with adaptive vss observer
Electrical Engineering in Japan, 1991 AbstractThe conventional sliding mode control or variable structure control (VSC) of a nonlinear uncertain system is well known for its robust property and simplicity of control law. However, the use of either is permitted only on the assumption that the upper bound of parameter variation or nonlinearity is known and that the complete information about
Yi-feng Chen, Tsutomu Mita
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Molecular Oncology, EarlyView.In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico +5 more
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Molecular Oncology, EarlyView.This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault +12 more
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Molecular Oncology, EarlyView.The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim +17 more
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Nihon Kikai Gakkai ronbunshu, 2020 In this paper, we present a new design of the robust observer called integral sliding mode observer (ISM observer) for nonlinear strict feedback systems.
Nobuhito UENISHI, Tomoaki KOBAYASHI
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