Results 31 to 40 of about 5,145 (265)

A Robust Observer-Based Control Strategy for n-DOF Uncertain Robot Manipulators with Fixed-Time Stability

Sensors, 2021
In this paper, a robust observer-based control strategy for n-DOF uncertain robot manipulators with fixed-time stability was developed. The novel fixed-time nonsingular sliding mode surface enables control errors to converge to the equilibrium point ...
Anh Tuan Vo, Thanh Nguyen Truong, Hee-Jun Kang, Mien Van   +3 more
doaj   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Output current observation and control of grid-connected modular multilevel converter using a simplified super twisting algorithm sliding mode

Results in Engineering
This paper presents a method for observing and controlling the output current of a grid-connected Modular Multilevel Converter (MMC) using a Simplified Super Twisting Algorithm-Sliding Mode (SSTA-SM).
Imane Alia, Imad Merzouk, Mehamed Mounir Rezaoui, Hegazy Rezk, Abderezak Lashab   +4 more
doaj   +1 more source

Disturbance Observer-Based Discrete Sliding-Mode Control for a Marine Diesel Engine with Variable Sampling Control Technique

Journal of Control Science and Engineering, 2020
This paper proposes a disturbance observer-based discrete sliding-mode control scheme with the variable sampling rate control for the marine diesel engine speed control in the presence of system uncertainties and disturbances.
Xuemin Li, Yufei Liu, Haoyu Shu, Runzhi Wang, Yunlong Yang, Chunyue Feng   +5 more
doaj   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

A non-singular sliding mode controller for quadrotor attitude with predefined time disturbance observer

Advances in Mechanical Engineering
In this paper, a quadrotor attitude controller based on a predefined time disturbance observer and non-singular predefined time sliding mode is proposed to reject unknown disturbances.
Jingxin Dou, Dongwu Xie, Yingliang Wu, Ti Zhang   +3 more
doaj   +1 more source

Disturbance attenuation–based sliding mode control with disturbance observer for mismatched uncertain system

Advances in Mechanical Engineering, 2017
A disturbance attenuation–based sliding mode control approach with an extended disturbance observer is proposed for systems with mismatched uncertainties. A novel adaptive sliding surface consisting of the disturbance estimation is presented to eliminate
Jianguo Guo, Yuchao Liu, Cheng Cheng, Jun Zhou   +3 more
doaj   +1 more source

Time-Delay Luenberger Observer Design for Sliding Mode Control of Nonlinear Markovian Jump Systems via Event-Triggered Mechanism

Machines, 2021
This paper is focused on the stabilization of Takagi–Sugeno fuzzy model-based Markovian jump systems with the aid of a delayed state observer. Due to network-induced constraints in the communication channel, a delay partition method combined with an ...
Min Cheng, Chunyang Zhang, Jin Qiu, Zhengtian Wu, Qing Gao   +4 more
doaj   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source