Results 81 to 90 of about 62,407 (298)

Monitoring of circulating tumor DNA allows early detection of disease relapse in patients with operable breast cancer

open access: yesMolecular Oncology, EarlyView.
Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad   +35 more
wiley   +1 more source

Controlling the Biological Invasion of a Commercial Fishery by a Space Competitor: A Bioeconomic Model with Reference to the Bay of St-Brieuc Scallop Fishery [PDF]

open access: yes
This paper presents a bioeconomic model of a commercial fishery facing biological invasion by an alien species acting as a space competitor for the native species.
Boncoeur, Jean, Fresard, Marjolaine
core   +1 more source

Impact of Flower Harvesting on the Salt Marsh Plant \u3cem\u3eLimonium carolinianum\u3c/em\u3e [PDF]

open access: yes, 2002
Because of the potentially detrimental effects of seed production on adult survivorship and growth, moderate flower harvesting may have little negative impact on population growth of long-lived perennial plants such as Limonium carolinianum (Walter ...
Baltzer, Jennifer L.   +4 more
core   +1 more source

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola   +12 more
wiley   +1 more source

The Vermilion River basin : an inventory of the region's resources [PDF]

open access: yes, 2000
published or submitted for ...
Post, Susan L.
core  

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

open access: yesMolecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone   +11 more
wiley   +1 more source

Eelgrass Habitat Creation in Nantucket Harbor, Massachusetts [PDF]

open access: yes, 2012
In response to eelgrass habitat losses associated with development and marine activities in and around Nantucket Harbor, a plan to restore a meadow by transplanting eelgrass to previously vegetated areas was developed in conjunction with the Nantucket ...
Burdick, David M   +2 more
core   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

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