Results 91 to 100 of about 187,260 (305)

Probability analysis of undrained clay slope stability considering strength anisotropy and heterogeneous rotated anisotropy

open access: yesFrontiers in Earth Science
Strength anisotropy and heterogeneous rotated anisotropy are prevalent phenomena in natural slopes. Previous studies have underscored their significance in slope stability analysis.
Wei Cao   +4 more
doaj   +1 more source

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

open access: yesMolecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy   +10 more
wiley   +1 more source

The determination of joint roughness coefficient using three-dimensional models for slope stability analysis

open access: yes, 2013
Joint roughness coefficient (JRC) is one of the important parameters to determine shear strength of joints. JRC values are generally measured using profile gauges and estimated by comparing the surface profiles with typical roughness profiles. Therefore,
Poropat, G.   +2 more
core  

Search For Critical Slip Surface In Slope Stability Analysis By Spline-Based Ga Method [PDF]

open access: yes, 2008
The stability of a soil slope is usually analyzed by limit equilibrium methods, in which the identification of the critical slip surface is of principal importance.
孙建平   +3 more
core   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

Slope stability analysis considering the strength anisotropy of c-φ soil. [PDF]

open access: yesSci Rep, 2022
He Y   +5 more
europepmc   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

open access: yesMolecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder   +10 more
wiley   +1 more source

Stability analysis of water-filled dump slope under the couple effect of seepage and damage

open access: yes, 2012
The stability problem of water-filled dump slope becomes one of the geotechnical engineering problems needed to be resolved. Especially, the couple effect of seepage and damage has a great influence on the dump slope.
吕祥锋   +3 more
core  

Probability analysis of slope stability

open access: yes, 1999
The ability of geotechnical engineers to accurately model slope performance is compromised by a variety of factors. The net result of these considerations is that the exact behavior of slopes cannot be accurately predicted.
Peterson, Jennifer Lynn
core   +1 more source

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