Results 101 to 110 of about 187,260 (305)

Correlations between factor of safety with distributed load and crest length – Zariwam landslide as case study

Geology, Ecology, and Landscapes
This paper examines the impact on Factor of Safety (FS) value due to the variation in distributed load (LD), Crest length (CL), shear strength (τ), and shear stress (σ) both in seismic and non-seismic conditions.
Muhammad Israr Khan
doaj   +1 more source

A novel empirical classification method for weak rock slope stability analysis. [PDF]

Sci Rep, 2022
Azarafza M, Hajialilue Bonab M, Derakhshani R.   +2 more
europepmc   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

Molecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht, Sameer Gupta, Amrita Chaurasia, Manisha Sachan   +3 more
wiley   +1 more source

Three-Dimensional Analysis of Complex Rock Slope Stability Affected by Fault and Weak Layer Based on FESRM

Advances in Civil Engineering, 2019
Slope stability analysis is the most important problem in slope engineering design and construction. Open-pit slope often spans several strata, many of which are relatively weak. There may be faults and weak layers across the whole rock.
Yang Li, Ling Yu, Weidong Song, Tianhong Yang   +3 more
doaj   +1 more source

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

Molecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski, Liudmyla Dolinchuk, Michał Jerzak, Albert Gandurski, Tomasz Grochowski, Weronika Wojtyś, Maciej Zadrożny, Wojciech Kaźmierczak, Małgorzata Lenarcik, Marta Matejak‐Górska, Radosław Samsel, Tomasz Olesiński, Dawid Walerych   +12 more
wiley   +1 more source

Slope-stability assessments using finite-element limit-analysis methods

, 2017
This paper utilizes finite-element limit-analysis methods to investigate the stability of slopes of various properties and in nature. Specifically, a slope with a soft (weak material) band, a postquake slope, and rock slopes were investigated.
AJ Li (14531738), AV Lyamin (15815252), A Schmid (8682288), K Lim (7778960)   +3 more
core  

Análise de estabilidade bi e tridimensional de talude estabilizado em solo grampeado [PDF]

, 2006
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro Tecnológico. Programa de Pós-Graduação em Engenharia Civil.O emprego da técnica do reforço de solos para a estabilização de taludes, naturais ou não, através do grampeamento do solo,
Oliveira, Vanessa Scoz
core  

Stability Analysis of Cut Slope Using RMR and SMR

, 2022
The Planjan - Tepus road is built on a slightly steep karst morphology, necessitating slope excavation works. Slope stability is one of the elements to consider, particularly in slope excavation work.
Indrawan, I Gde Budi, Barianto, Didit Hadi, Astuti, Tri Puji   +2 more
core   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source