Results 81 to 90 of about 763,323 (299)

Preliminary Analysis of Slope Stability in Kuok and Surrounding Areas [PDF]

, 2016
The level of slope influenced by the condition of the rocks beneath the surface. On high level of slopes, amount of surface runoff and water transport energy is also enlarged.
Choanji, T. (Tiggi), Putra, D. B. (Dewandra)   +1 more
core   +3 more sources

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

Analysis of Slope Stability Using Limit Equilibrium

Bulletin of the Polytechnic Institute of Jassy: Constructions, Architechture Section, 2010
In achievement of slope load sustainability using mixed soil technique, is considered acceptable the method for slope construction technology. This paper deals with evaluation of mixed soil technique for construction of stable slope and proves the soil ...
Abdoullah Namdar
doaj  

Sensitivity Analysis of Influencing Factors of Building Slope Stability Based on Orthogonal Design and Finite Element Calculation

E3S Web of Conferences, 2018
In order to study the sensitivity of factors affecting the homogeneous building slope stability, the orthogonal test design method and shear strength reduction finite element method were used.
Jin-kui RUAN, Wei-wei ZHU
doaj   +1 more source

Long surface wave instability in dense granular flows [PDF]

, 2003
In this paper we present an experimental study of the long surface wave instability that can develop when a granular material flows down a rough inclined plane.
Forterre, Y., Pouliquen, O.
core   +3 more sources

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source

Dealing with deep uncertainties in landslide modelling for disaster risk reduction under climate change [PDF]

, 2016
Landslides have large negative economic and societal impacts, including loss of life and damage to infrastructure. Slope stability assessment is a vital tool for landslide risk management, but high levels of uncertainty often challenge its usefulness ...
Almeida, Susana, Holcombe, Liz, Pianosi, Francesca, Wagener, Thorsten   +3 more
core   +2 more sources

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Analysis of slope failure at Maran highway using slope/w software [PDF]

, 2011
Analysis towards certain slope at Malaysia is important due to many tragedy occurred effect by the slope failure. The purpose of this study is to analyze the slope stability at KM 99 and 101, Maran Highway that carried out by using computer simulation ...
Annas Robani, Aminudin
core  

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source