Results 91 to 100 of about 435,657 (302)

Sub-kHz lasing of a CaF_2 Whispering Gallery Mode Resonator Stabilized Fiber Ring Laser

open access: yes, 2012
We utilize a high quality calcium fluoride whispering-gallery-mode resonator to stabilize a simple erbium doped fiber ring laser with an emission frequency of 196 THz (wavelenght 1530 nm) to a linewidth below 650 Hz.
Alnis   +30 more
core   +1 more source

The singular perturbation of surface tension in Hele-Shaw flows [PDF]

open access: yes, 2000
Morphological instabilities are common to pattern formation problems such as the non-equilibrium growth of crystals and directional solidification. Very small perturbations caused by noise originate convoluted interfacial patterns when surface tension is
Ceniceros, Hector D., Hou, Thomas Y.
core   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung   +17 more
wiley   +1 more source

Multi-Criterion Stability Evaluation and Surface Boundary Method for Slopes

open access: yesAdvances in Civil Engineering
Slope failure generally starts from a single point, where a local failure surface forms, and then progresses to the overall failure. Based on this behavior, this paper proposes a multi-criterion stability evaluation approach for describing progressive ...
Lier Lu   +3 more
doaj   +1 more source

Optimal mistuning for enhanced aeroelastic stability of transonic fans [PDF]

open access: yes, 1983
An inverse design procedure was developed for the design of a mistuned rotor. The design requirements are that the stability margin of the eigenvalues of the aeroelastic system be greater than or equal to some minimum stability margin, and that the mass ...
Crawley, E. F., Hall, K. C.
core   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon   +9 more
wiley   +1 more source

Stability Evaluation Method for Rock Slope-Anchorage Systems Based on Genetic Algorithms and Discrete Element Analysis

open access: yesApplied Sciences
With the increasing scale of infrastructure projects in sectors such as hydraulics and transportation, coupled with the widespread adoption of anchorage support technologies, numerous rock slope anchorage systems have been established.
Peng Xia, Bowen Zeng, Yiheng Pan
doaj   +1 more source

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

open access: yesMolecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli   +7 more
wiley   +1 more source

Slope stability evaluation using backpropagation neural networks and multivariate adaptive regression splines

open access: yesOpen Geosciences, 2020
Slope stability assessment is a critical concern in construction projects. This study explores the use of multivariate adaptive regression splines (MARS) to capture the intrinsic nonlinear and multidimensional relationship among the parameters that are ...
Liao Zhihao, Liao Zhiwei
doaj   +1 more source

Evaluation of topography site effect in slope stability under dynamic loading

open access: yes, 2013
International audienceThe slope topography site effect is a phenomenon in which the seismic ground motion is amplified at the crest of the slope. This effect can damage structures and can even cause slope instabilities.
Cojean, Roger   +2 more
core   +1 more source

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