Results 71 to 80 of about 73,922 (300)
The bench slope within an open-pit coal mine plays an important supporting role for coal resource production and transportation. The stability evaluation of the slope is of great significance in guiding continuous mining operations within the mine.
Zhiguo LI +6 more
doaj +1 more source
In order to accurately evaluate the stability of the slope and reduce the risk of landslides,taking the Jiangjiatang slope project in Xingshan,Hubei as an example,this paper selects four first-level indexes namely topography and geomorphology,geological ...
ZHOU Jintao
doaj
Image-Data-Driven Slope Stability Analysis for Preventing Landslides Using Deep Learning
Landslides account for approximately 5% of natural disasters resulting in significant socio-economic impacts. As a major infrastructure issue, slope stability has been traditionally analyzed with multiple deterministic and probabilistic methods to
Behnam Azmoon +3 more
doaj +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Application of Slope Mass Rating System In Slope Stability Class Evaluation
The rock slope stability analysis is a challenging task in geotechnical engineering. The metasedimentary cut slope at Putrajaya-Cyberjaya Link was assessed using Slope Mass Rating (SMR) system in this study. The results of SMR calculation obtained in this study is 23.3.
Rasyikin Roslan* +4 more
openaire +1 more source
Diversity and complexity in neural organoids
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
The human gut microbiome across the life course
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
wiley +1 more source
Modelling shallow landslides: the importance of hydrological controls and lateral reinforcement [PDF]
Shallow landslides are important as geomorphic agents of erosion, sources of catchment sediment and potential hazards to life and infrastructure. The importance of these mass movements is difficult to define using solely field- based approaches because ...
Milledge, David Graham
core

