Results 71 to 80 of about 7,834,713 (261)

The extent and an analysis of shallow failures on the slopes of highway earthworks [PDF]

open access: yes, 1991
The reported incidences of shallow failures on the slopes of highway earthworks have increased in recent years. This Thesis includes a study of the extent of this problem, the likely factors contributing to failure, and presents the results of ...
Perry, John
core  

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

open access: yesFEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav   +2 more
wiley   +1 more source

Multi-Criterion Stability Evaluation and Surface Boundary Method for Slopes

open access: yesAdvances in Civil Engineering
Slope failure generally starts from a single point, where a local failure surface forms, and then progresses to the overall failure. Based on this behavior, this paper proposes a multi-criterion stability evaluation approach for describing progressive ...
Lier Lu   +3 more
doaj   +1 more source

Prospecting the protein design landscape

open access: yesFEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona   +4 more
wiley   +1 more source

Slope stability analysis of a small intermittent failure

open access: yes, 2015
During significant precipitation events water that does not directly run off\ud infiltrates the soil. If the soils are thin or overlie an impermeable layer, the water will\ud percolate to the impermeable layer and build-up forming a perched water table ...
Adams, Chloe
core  

Slope Stability Prediction Based on CCO-Optimized XGBoost Model

open access: yesEng
Achieving rapid and accurate prediction of slope stability is a key scientific issue in slope engineering. However, slope stability is governed by multi-factor coupling effects and exhibits strong nonlinear characteristics, and traditional slope ...
Changqing Du   +4 more
doaj   +1 more source

Analysis and Development Trend of Slope Stability Calculation Theory and Evaluation Criteria

open access: yesMeikuang Anquan, 2020
Landslide is one of the most common geological hazards in China. After nearly one hundred years of research by many scholars, the theory of slope stability calculation and evaluation, safety prevention and control measures and prediction theory have made
SUN Shiguo, YU Xi, DONG Yanfei
doaj   +1 more source

Artificial molecular machines and motors—Design and control of nanoscale motion

open access: yesFEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

Stability Evaluation Method for Rock Slope-Anchorage Systems Based on Genetic Algorithms and Discrete Element Analysis

open access: yesApplied Sciences
With the increasing scale of infrastructure projects in sectors such as hydraulics and transportation, coupled with the widespread adoption of anchorage support technologies, numerous rock slope anchorage systems have been established.
Peng Xia, Bowen Zeng, Yiheng Pan
doaj   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

open access: yesFEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise   +5 more
wiley   +1 more source

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