Results 81 to 90 of about 73,922 (300)
FEBS Letters, EarlyView.This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley +1 more source
An evaluation method of open-pit slope stability based on Poset theory
Geomechanics and Geophysics for Geo-Energy and Geo-ResourcesTo achieve an objective and reasonable judgment on slope stability, the partially ordered set (Poset) theory is applied to the slope stability evaluation against the engineering background of an open pit slope.
Juyu Jiang +5 more
doaj +1 more source
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
FEBS Letters, EarlyView.An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
An Evaluation of the Application of Plasma Arc Vitrification to Improve the Strength of Weak Soil and Weathered Rock [PDF]
, 2002 The applicability of Plasma Arc Vitrification (PAV) to improve the strength of weak soils and weathered rock is investigated. Destructive and non-destructive tests are conducted in the field along with laboratory testing to estimate the physical and ...
Nash, Andrew Alan
core
FEBS Letters, EarlyView.We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Multi-Criterion Stability Evaluation and Surface Boundary Method for Slopes
Advances in Civil EngineeringSlope failure generally starts from a single point, where a local failure surface forms, and then progresses to the overall failure. Based on this behavior, this paper proposes a multi-criterion stability evaluation approach for describing progressive ...
Lier Lu +3 more
doaj +1 more source
Slope Stability Prediction Based on CCO-Optimized XGBoost Model
EngAchieving rapid and accurate prediction of slope stability is a key scientific issue in slope engineering. However, slope stability is governed by multi-factor coupling effects and exhibits strong nonlinear characteristics, and traditional slope ...
Changqing Du +4 more
doaj +1 more source