Results 51 to 60 of about 117,118 (314)

Transcriptome sequencing analysis of the role of miR-499-5p and SOX6 in chicken skeletal myofiber specification

open access: yesFrontiers in Genetics, 2022
MicroRNAs (miRNAs) might play critical roles in skeletal myofiber specification. In a previous study, we found that chicken miR-499-5p is specifically expressed in slow-twitch muscle and that its potential target gene is SOX6. In this study, we performed
Yi-Fan Liu   +20 more
doaj   +1 more source

Voluntary activation of human knee extensors measured using transcranial magnetic stimulation [PDF]

open access: yes, 2009
The aim of this study was to determine the applicability and reliability of a transcranial magnetic stimulation twitch interpolation technique for measuring voluntary activation of a lower limb muscle group.
Ross, Emma   +10 more
core   +1 more source

LncRNA-TBP mediates TATA-binding protein recruitment to regulate myogenesis and induce slow-twitch myofibers

open access: yesCell Communication and Signaling, 2023
Background Skeletal muscle is comprised of heterogeneous myofibers that differ in their physiological and metabolic parameters. Of these, slow-twitch (type I; oxidative) myofibers have more myoglobin, more mitochondria, and higher activity of oxidative ...
Manting Ma   +7 more
doaj   +1 more source

Regulation of skeletal muscle plasticity by the transcriptional coregulators PGC-1α and NCoR1 [PDF]

open access: yes, 2013
Skeletal muscle plasticity is regulated by a wide range of factors, among which environmental stimuli such as exercise play a central role. Importantly, changes in skeletal muscle phenotype exert a direct impact on health and risk to premature death.
Pérez-Schindler, Joaquín
core   +1 more source

Quantitative analysis of dystrophin in fast‐ and slow‐twitch mammalian skeletal muscle [PDF]

open access: yesFEBS Letters, 1992
The relative tissue content of dystrophin has been evaluated in the slow‐twitch soleus (primarily type I fibers) and fast‐twitch vastus lateralis (primarily type IIb filbers) muscles of the rat and mouse, as well as in human biopsy samples from the vastus lateralis and gluteus maximus muscles, using a sensitive immunochemical assay.
Ho-Kim, My-Anh, Rogers, Peter A.
openaire   +2 more sources

Characterization of RyR1-slow, a ryanodine receptor specific to slow-twitch skeletal muscle [PDF]

open access: yes, 2000
Two distinct skeletal muscle ryanodine receptors (RyR1s) are expressed in a fiber type–specific manner in fish skeletal muscle (11). In this study, we compare [3H]ryanodine binding and single channel activity of RyR1-slow from fish slow-twitch skeletal ...
Barbara A. Block   +4 more
core   +1 more source

Neuromuscular fatigability during repeated-sprint exercise in male athletes [PDF]

open access: yes, 2015
Purpose - To determine the pattern of neuromuscular fatigability that manifests during repeated sprint running exercise. Methods - Twelve male participants (mean ± SD age, 25 ± 6 yr; stature, 180 ± 7 cm; body mass, 77 ± 7 kg), currently training and ...
Thomas, Kevin   +3 more
core   +1 more source

Eicosapentaenoic acid increases proportion of type 1 muscle fibers through PPARδ and AMPK pathways in rats

open access: yesiScience
Summary: Muscle fiber type composition (% slow-twitch and % fast-twitch fibers) is associated with metabolism, with increased slow-twitch fibers alleviating metabolic disorders.
Yusuke Komiya   +11 more
doaj   +1 more source

Natural Frequencies of Levodopa‐Induced Dyskinesia in Parkinson's Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Abnormal involuntary movements, known as dyskinesias, are common complications of levodopa treatment in patients with Parkinson's disease and can significantly impair quality of life. The underlying pathophysiology remains unclear, and current therapeutic options are limited.
Ioannis U. Isaias   +3 more
wiley   +1 more source

EXERCISE MYOPATHY: CHANGES IN MYOFIBRILS OF FAST-TWITCH MUSCLE FIBRES [PDF]

open access: yes, 2014
The purpose of the present study was to determine the relationships between the changes of myofibrils in fast-twitch oxidative-glycolytic (type IIA) fibres and fast-twitch glycolytic (type IIB) muscle fibres, protein synthesis and degradation rate in ...
M. Umnova, T. Seene, P. Kaasik
core   +1 more source

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