Slow-Twitch Fiber Proportion in Skeletal Muscle Correlates With Insulin Responsiveness [PDF]
The metabolic syndrome, characterized by central obesity with dyslipidemia, hypertension, and hyperglycemia, identifies people at high risk for type 2 diabetes.Our objective was to determine how the insulin resistance of the metabolic syndrome is related to muscle fiber composition.Thirty-nine sedentary men and women (including 22 with the metabolic ...
Stuart, Charles A. +7 more
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Effects of Resistance Exercise on Slow-Twitch Soleus Muscle of Infarcted Rats
Although current guidelines recommend resistance exercise in combination with aerobic training to increase muscle strength and prevent skeletal muscle loss during cardiac remodeling, its effects are not clear. In this study, we evaluated the effects of resistance training on cardiac remodeling and the soleus muscle in long-term myocardial infarction ...
Lidiane Moreira Souza +14 more
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A minimally invasive optical window enables stable, long‐term imaging of peripheral nerves in vivo at single‐axon resolution. Dynamic processes of degeneration, regeneration, and cellular remodeling are visualized across multiple time scales within the same nerve region, providing a unique platform to study a variety of anatomical and molecular events ...
Igor D. Luzhansky +15 more
wiley +1 more source
The slow sarco/endoplasmic reticulum Ca2+-ATPase declines independently of slow myosin in soleus muscle of diabetic rats [PDF]
The sarcoplasmic reticulum Ca2+-ATPase (SERCA) isoforms are normally expressed in coordination with the corresponding myosin heavy chain (MyHC) isoforms in the fibers of skeletal muscle but this coordination is often disrupted in pathological conditions.
Rácz, Gábor +7 more
core
The PGC-1 coactivators promote an anti-inflammatory environment in skeletal muscle in vivo [PDF]
The peroxisome proliferator-activated receptor γ coactivator 1α (PGC-1α) is abundantly expressed in trained muscles and regulates muscle adaptation to endurance exercise. Inversely, mice lacking a functional PGC-1α allele in muscle exhibit reduced muscle
Handschin, Christoph +7 more
core +1 more source
Abstract Intermittent hypobaric hypoxia (IHH) enhances oxygen transport, muscle metabolism, and cardiovascular health; however, the combined effects of hypobaria and cold are less well understood. Exposure to these stressful environmental factors, even intermittently, can affect skeletal muscle due to its plasticity, thereby altering its metabolic and ...
Garoa Santocildes +3 more
wiley +1 more source
Alterations in Z-line thickness following fast motoneuron transplantation onto slow twitch skeletal muscle fibers [PDF]
Differentiation of skeletal muscle fibers into fast and slow twitch appears to be under control of the stimulation pattern imparted by motoneurons innervating these muscle fibers. Fast twitch muscle fibers receive intense stimulation for brief periods of
Bishop, Derron L.
core
Characterization of fast-twitch and slow-twitch skeletal muscles of calsequestrin 2 (CASQ2)-knock out mice: unexpected adaptive changes of fast-twitch muscles only [PDF]
This study investigates the functional role of calsequestrin 2 (CASQ2) in both fast-twitch and slow-twitch skeletal muscles by using CASQ2−/− mice; CASQ2 is expressed throughout life in slow-twitch muscles, but only in the developmental and neonatal ...
DE ROSA, EDITH +8 more
core +1 more source
Skeletal muscle contraction, which generates movement by pulling on the internal skeleton, is a distinctive mode of movement in vertebrates. Renowned for its flexibility, diversity, and efficiency, this mode of movement is significant for the individual ...
Huan WANG, Shufang LIU
doaj +1 more source
Efficiency of Fast- and Slow-Twitch Muscles of the Mouse Performing Cyclic Contractions [PDF]
ABSTRACT The mechanical efficiency of mouse fast- and slow-twitch muscle was determined during contractions involving sinusoidal length changes. Measurements were made of muscle length, force production and initial heat output from bundles of muscle fibres in vitro at 31°C.
openaire +4 more sources

