Results 71 to 80 of about 1,504,818 (288)
Scientific Reports, 2022 Trk-fused gene (TFG) mutations have been identified in patients with several neurodegenerative diseases. In this study, we attempted to clarify the effects of TFG deletions in motor neurons and in muscle fibers, using tissue-specific TFG knockout (vMNTFG
Takeshi Yamamotoya +11 more
doaj +1 more source
Anatomy of the Soft Palate and Its Role in Upper Airway Function: A Narrative Review
Clinical Anatomy, EarlyView.ABSTRACT The soft palate is a complex anatomical structure, located at the posterior aspect of the oral and nasal cavities, able to dynamically create valve closure of the nasal and the oral cavities. Its precise movement is critical for speech, swallowing, and respiration. Despite its functional importance, detailed characterization of its constituent
James C. D. Miller +4 more
wiley +1 more source
Neuromuscular fatigability during repeated-sprint exercise in male athletes [PDF]
, 2015 Purpose - To determine the pattern of neuromuscular fatigability that manifests during repeated sprint running exercise. Methods - Twelve male participants (mean ± SD age, 25 ± 6 yr; stature, 180 ± 7 cm; body mass, 77 ± 7 kg), currently training and ...
Thomas, Kevin +3 more
core +1 more source
Fhod3 in zebrafish supports myofibril stability during growth of embryonic skeletal muscle
Developmental Dynamics, EarlyView.Abstract Background Actin filament organization in cardiomyocytes critically depends on the formin Fhod3, but a role for Fhod3 in skeletal muscle development has not yet been described. Results We demonstrate here that in zebrafish mutated for one of two fhod3 paralog genes, fhod3a, skeletal muscle of the trunk appears normal through 2 days post ...
Aubrie Russell +3 more
wiley +1 more source
Cell ReportsSummary: Myocytes are exceptionally long-lived cells that must maintain proteome integrity over decades while adjusting for changes in functional output and metabolic demand.
Jack Gugel +10 more
doaj +1 more source
The PGC-1 coactivators promote an anti-inflammatory environment in skeletal muscle in vivo [PDF]
, 2015 The peroxisome proliferator-activated receptor γ coactivator 1α (PGC-1α) is abundantly expressed in trained muscles and regulates muscle adaptation to endurance exercise. Inversely, mice lacking a functional PGC-1α allele in muscle exhibit reduced muscle
Handschin, Christoph +7 more
core +1 more source
Epilepsia Open, EarlyView.Abstract Spatial memory, the aspect of memory involving encoding and retrieval of information regarding one's environment and spatial orientation, is a complex biological function incorporating multiple neuronal networks. Hippocampus‐dependent spatial memory is not innate and emerges during development in both humans and rodents.
Gregory L. Holmes
wiley +1 more source
International Journal of Women's Health, 2023 Xiaolei Chi,1,2,* Shushu Yu,1,2,* Kun Zhu,3 Yiyao Chen,1,2 Yi Chu,1,2 Xinliang Chen1,2 1Department of Obstetrics and Gynecology, International Peace Maternity and Child Health Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai,
Chi X +5 more
doaj
Distinct signal transductions in fast- and slow- twitch muscles upon denervation
Physiological Reports, 2018 Denervation induces skeletal muscle atrophy, which primarily impairs oxidative slow twitch fibers. The underlying mechanism of this phenomenon, however, remains to be addressed. We hypothesize that denervation-induced fiber-specific atrophy may result from the distinct activities of different signaling pathways that are involved in protein synthesis ...
Gao, Hongbo, Li, Yi‐Fan
openaire +2 more sources
Epilepsy syndromes classification
Epilepsia Open, EarlyView.Abstract Epilepsy syndromes are distinct electroclinical entities which have been recently defined by the International League Against Epilepsy Nosology and Definitions Task Force. Each syndrome is associated with “a characteristic cluster of clinical and EEG features, often supported by specific etiologic findings”.
Elaine C. Wirrell +4 more
wiley +1 more source