Results 81 to 90 of about 1,504,818 (288)

Pre-exercise casein peptide supplementation enhances endurance training-induced mitochondrial enzyme activity in slow twitch muscle, but not fast twitch muscle of high fat diet-fed mice

Journal of Physical Fitness and Sports Medicine, 2015
To establish an efficient method of enhancing mitochondrial biogenesis, we investigated the effect of casein peptide supplementation. The aim of this study was to examine whether oral casein peptide ingestion enhances exercise-induced mitochondrial ...
Yutaka Matsunaga, Yuki Tamura, Yumiko Takahashi, Hiroyuki Masuda, Daisuke Hoshino, Yu Kitaoka, Noriko Saito, Hirohiko Nakamura, Yasuhiro Takeda, Hideo Hatta   +9 more
doaj   +1 more source

Effects of Captan, a fungicide, on mammalian slow‐twitch muscle

The FASEB Journal, 2013
The population exposure to pesticides is dramatically increasing in the last few decades because of the widespread uncontrolled use of pesticides especially in the developing countries. In our study, we examine the effect of 6 mg/kg of Captan, a fungicide, mixed with diet, on body weight, muscle mass, proteins content and contractile response of slow ...
Walaa Darwich, Wiam Ramadan, Hassan Khachfe, Hanane Akhdar, Wassim Rammal, Marwan Koubaissi, Lina Sabra, Veronique Bach, Wissam H Joumaa   +8 more
openaire   +1 more source

Genetic epilepsies with myoclonic seizures: Mechanisms and syndromes

Epilepsia Open, EarlyView.
Abstract Genetic epilepsy with myoclonic seizures encompasses a heterogeneous spectrum of conditions, ranging from benign and self‐limiting forms to severe, progressive disorders. While their causes are diverse, a significant proportion stems from genetic abnormalities.
Antonietta Coppola, Marica Rubino, Antonella Riva, Pasquale Striano   +3 more
wiley   +1 more source

Exhausting treadmill running causes dephosphorylation of sMLC2 and reduced level of myofilament MLCK2 in slow twitch rat soleus muscle [PDF]

, 2015
Myosin light chain 2 (MLC2) is a small protein in the myosin complex, regulating muscle contractile function by modulating Ca2+ sensitivity of myofilaments.
Lunde, Per Kristian, Sjaastad, Ivar, Lunde, Ida G, Aronsen, Jan Magnus, Hortemo, Kristin Halvorsen, Sejersted, Ole M, Lunde, Ida Gjervold   +6 more
core   +1 more source

Precision therapies for genetic epilepsies in 2025: Promises and pitfalls

Epilepsia Open, EarlyView.
Abstract By targeting the underlying etiology, precision therapies offer an exciting paradigm shift to improve the stagnant outcomes of drug‐resistant epilepsies, including developmental and epileptic encephalopathies. Unlike conventional antiseizure medications (ASMs) which only treat the symptoms (seizures) but have no effect on the underlying ...
Shuyu Wang, Emilio Perucca, Samuel F. Berkovic, Piero Perucca   +3 more
wiley   +1 more source

Ionic currents in slow twitch skeletal muscle in the rat.

The Journal of Physiology, 1980
1. The ionic currents in slow fibres isolated from rat soleus muscle have been studied under voltage‐clamp conditions with a double sucrose‐gap method and the results are compared to those obtained from fast fibres isolated from the iliacus muscle. 2. The mean value of the resting potential in slow fibres is ‐70 mV.
A, Duval, C, Léoty
openaire   +3 more sources

Characterization of RyR1-slow, a ryanodine receptor specific to slow-twitch skeletal muscle

, 2000
Two distinct skeletal muscle ryanodine receptors (RyR1s) are expressed in a fiber type–specific manner in fish skeletal muscle (11). In this study, we compare [3H]ryanodine binding and single channel activity of RyR1-slow from fish slow-twitch skeletal ...
Barbara A. Block, Le Xu, Jeffery Morrissette, Gerhard Meissner, Alexandra Nelson   +4 more
core   +1 more source

Absence seizures: Update on signaling mechanisms and networks

Epilepsia Open, EarlyView.
Abstract Absence seizures (AS) are a hallmark of genetic generalized epilepsies (GGE), characterized by brief episodes of impaired consciousness accompanied by electroencephalographic spike‐and‐wave discharges (SWDs). Traditionally attributed to cortico‐thalamo‐cortical (CTC) dysrhythmia, emerging evidence suggests a more intricate pathophysiological ...
Ozlem Akman, Filiz Onat
wiley   +1 more source

Strenuous Acute Exercise Induces Slow and Fast Twitch-Dependent NADPH Oxidase Expression in Rat Skeletal Muscle

Antioxidants, 2020
The enzymatic complex Nicotinamide Adenine Dinucleotide Phosphate (NADPH) oxidase (NOx) may be the principal source of reactive oxygen species (ROS). The NOX2 and NOX4 isoforms are tissue-dependent and are differentially expressed in slow-twitch fibers ...
Juliana Osório Alves, Leonardo Matta Pereira, Igor Cabral Coutinho do Rêgo Monteiro, Luiz Henrique Pontes dos Santos, Alex Soares Marreiros Ferraz, Adriano Cesar Carneiro Loureiro, Crystianne Calado Lima, José Henrique Leal-Cardoso, Denise Pires Carvalho, Rodrigo Soares Fortunato, Vânia Marilande Ceccatto   +10 more
doaj   +1 more source

Homer 2 antagonizes protein degradation in slow-twitch skeletal muscles

American Journal of Physiology-Cell Physiology, 2013
Homer represents a new and diversified family of proteins made up of several isoforms. The presence of Homer isoforms, referable to 1b/c and 2a/b, was investigated in fast- and slow-twitch skeletal muscles from both rat and mouse. Homer 1b/c was identical irrespective of the muscle, and Homer 2a/b was instead characteristic of the slow-twitch ...
Bortoloso E, MEGIGHIAN, ARAM, Furlan S, GORZA, LUISA, VOLPE, POMPEO   +4 more
openaire   +3 more sources