Results 51 to 60 of about 377,857 (257)
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
That Was Then, This Is Wow: A Case for Critical Information Literacy Across the Curriculum
Communications in Information Literacy, 2020 This article applies a Writing across the Curriculum approach to Critical Library Instruction. The information landscape has drastically shifted over the past ten years, altering the ways we perform, interact with, access, and understand research.
Margaret Rose Torrell
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
New Journal of Physics, 2018 We study the structure of the elementary excitations and their propagation in chiral hybrid structure, comprising an array of two-level systems (TLSs) coupled to a one-dimensional photonic waveguide.
A V Yulin, I V Iorsh, I A Shelykh
doaj +1 more source
Slow Manand the Real: A Lesson in Reading and Writing
Journal of Literary Studies, 2009 Summary This article addresses the problems of reading Slow Man (Coetzee 2005) through tracking its engagement with various levels of the real as well as its representation of the complex relationship between author, narrator and character. The real difficulty that besets the writer trying to produce a story from an inchoate idea is explored through ...
openaire +3 more sources
FEBS Letters, EarlyView.Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas +3 more
wiley +1 more source
مجله علوم روانشناختی, 2019 Background: Functional education is one of the criteria and indicators of success and efficiency of education system in societies. The design and development of functional learning materials should be based on individual, family, group, and social ...
Hoorieh Poorhanifeh +2 more
doaj
Self-writing as a tool for change: the effectiveness of a psychotherapy using diary
Research in Psychotherapy, 2019 There is an abundance of literature investigating the relationship between self-writing and well-being in cases of trauma or life-changing events, but no such research has assessed the value of keeping a daily diary in promoting small changes, describing
Elena Faccio +2 more
doaj +1 more source
An optimizing technique for using MATLAB HDL coder
Bulletin of the National Research Centre, 2023 Background MathWorks has provided an invaluable tool for designing and implementing FPGAs. MATLAB HDL coder serves a dual purpose, providing a quick proof of concept on the one hand and providing the g an easy-to-use platform for testing and verification
Somaya Kayed, Ghada Elsayed
doaj +1 more source
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
FEBS Letters, EarlyView.Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source