Results 61 to 70 of about 381,109 (217)

Desideri, fallimenti, resistenze: figure femminili nella narrativa di J.M. Coetzee

Between, 2013
Desire is a constant presence in J.M. Coetzee's fiction. Coetzee's narrators unremittingly wonder about desire: the more their position is "authorial", the more these fictional characters' reflections on this issue are consciously bound to writing and ...
Giulia Zanfabro
doaj   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

SLOW HEALING: ENVIRONMENTAL AND SOCIAL JUSTICE IN UNBOWED: A MEMOIR

Ankara Üniversitesi Dil ve Tarih-Coğrafya Fakültesi Dergisi
In her autobiography Unbowed: A Memoir (2006), Wangari Maathai, a political activist and Nobel Peace Prize winner, depicts environmental and political struggle against the legacies of colonialism.
Hediye Özkan
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Envisioning a Reconceptualised Postgraduate Support in Research Writing Development for the Future: A Three-Legged Framework

African Journal of Inter-Multidisciplinary Studies
The slow progress of postgraduate students in South African higher education institutions has been linked to a lack of preparedness at the undergraduate level, supervision practices and research writing skills of students.
Nonhlanhla Patience Khumalo, †Khethiwe Dongwe   +1 more
doaj   +1 more source

Poetry as method – trying to see the world differently

Research for All, 2020
Research with communities, even co-produced research with a commitment to social justice, can be limited by its expression in conventional disciplinary language and format.
doaj   +2 more sources

Homais et le journal

Flaubert: Revue Critique et Génétique, 2017
In Madame Bovary the figure of Homais is inseparable from the newspaper, a marker that specifies him. This article aims to show that this double novelistic existence is subjected to the same logic of invalidity by the novelist: the chemist is the typical
Corinne Trichet
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Towards a systemic functional model for comparing forms of discourse in academic writing Towards a systemic functional model for comparing forms of discourse in academic writing

Ilha do Desterro, 2008
This article reports on research into the variation of texts across disciplines and considers the implications of this work for the teaching of writing.
Meriel Bloor
doaj   +2 more sources

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source