Results 1 to 10 of about 590 (96)
The Memory Inflation Response Against Spread-Defective CMV Requires Priming-Independent CD4<sup>+</sup> T Cell Help. [PDF]
Eur J ImmunolInducing memory inflation (MI) is a promising future vaccination strategy. We show that spread‐defective cytomegalovirus does not induce MI in the absence of CD4+ T cells. Support from CD4+ T cells can drive effector differentiation of MI cells, even late in the response, and contributes to long‐term response maintenance. ABSTRACT Memory inflation (MI)
Barton J +6 more
europepmc +2 more sources
Improved opioid prescribing in primary care: protocol for a cluster randomised pragmatic trial [PDF]
BMJ OpenIntroduction Opioid analgesic medications play a critical role in pain management but are associated with significant risks, including addiction. General practitioners in primary care account for a substantial proportion of opioid prescriptions, and ...
Jeanette Westman +6 more
doaj +2 more sources
Sambandet mellan sömnbesvär och smärta hos ungdomar
Sömn och Hälsa, 2023 Hos tonåringar påverkar sömnbesvär och smärta varandra ömsesidigt i en negativ spiral. Sömnbesvär påverkar smärta mer än vice versa och tonårsflickor är mer påverkade av sambandet, jämfört med tonårspojkar.
Tor Arnison
doaj +1 more source
Dynamic functional modulation of CD4+ T cell recall responses is dependent on the inflammatory environment of the secondary stimulus. [PDF]
PLoS Pathogens, 2014 The parameters that modulate the functional capacity of secondary Th1 effector cells are poorly understood. In this study, we employ a serial adoptive transfer model system to show that the functional differentiation and secondary memory potential of ...
Chulwoo Kim +2 more
doaj +1 more source
Barns upplevelser av att sova på sjukhus
Sömn och Hälsa, 2022 Många barn som vårdas inneliggande på sjukhus får inte tillräcklig med ostörd nattsömn. Sömntiden är kortare, sömnkvaliteten sämre och barn har fler uppvaknanden under natten på sjukhus jämfört med hemma.
Sanna Bark, Emmy Karlsson
doaj +1 more source
Kulturella Perspektiv, 2020 Our way of understanding children’s intelligence seems to be in transition: developments within ge- netic technology is approaching the science-fiction phenomenon of "designer babies". Embryonic screening and new biomodifying technologies are mak-
Kristofer Hansson
doaj +1 more source
European Journal of Immunology, Volume 53, Issue 11, November 2023., 2023 This article provides state‐of‐the‐art protocols for identification, visualization and quantitative analyses of dendritic cell subsets in tissues by different immunofluorescence microscopy approaches. Abstract This article is part of the Dendritic Cell Guidelines article series, which provides a collection of state‐of‐the‐art protocols for the ...
Felix Bayerl +18 more
wiley +1 more source
Immunology, Volume 170, Issue 2, Page 214-229, October 2023., 2023 Autoimmune hepatitis (AIH) is marked by autoantibodies and hepatic infiltration of B cells and plasma cells, possibly indicating a pathogenic role of B cells in the disease. Using a spontaneous mouse model of AIH, we show that B cell depletion did not prevent disease manifestation.
David Lübbering +8 more
wiley +1 more source
European Journal of Immunology, Volume 52, Issue 6, Page 924-935, June 2022., 2022 HVEM‐ligand interaction has been proposed to have differential effects on T‐cell response. Here, we investigate the role of HVEM upon acute and chronic lymphocytic choriomeningitis virus (LCMV) infection. We found that HVEM expression is potently downregulated during the effector phase in virus‐specific T cells and remained dampened even after in the ...
Patrizia Diethelm +5 more
wiley +1 more source
Telefonerandets smarta praktiker
Kulturella Perspektiv, 2020 This article focus on smart habits established as the telephone became a mundane technology in Finland during the first part of the 20th century. Smartness is defined as tactical practices based on experience, knowledge, and situated cultural rationale ...
Fredrik Nilsson
doaj +1 more source