Results 11 to 20 of about 590 (96)
The ICOS–ICOSL pathway tunes thymic selection
We show that inducible T‐cell costimulator (ICOS) expression is upregulated as T cells mature in the thymus and that its ligand is expressed by important thymic antigen‐presenting cell populations that regulate negative selection of autoreactive T cells.
Mengqi Dong +7 more
wiley +1 more source
Low 2-dimensional CD4 T cell receptor affinity for myelin sets in motion delayed response kinetics. [PDF]
T cells recognizing self-peptides that mediate autoimmune disease and those that are responsible for efficacious immunity against pathogens may differ in affinity for antigen due to central and peripheral tolerance mechanisms.
Kristen M Rosenthal +6 more
doaj +1 more source
Guidelines for the use of flow cytometry and cell sorting in immunological studies (third edition)
Abstract The third edition of Flow Cytometry Guidelines provides the key aspects to consider when performing flow cytometry experiments and includes comprehensive sections describing phenotypes and functional assays of all major human and murine immune cell subsets.
Andrea Cossarizza +192 more
wiley +1 more source
This study analyzes antigen‐specific B and T lymphocytes in an adoptive transfer airway inflammation mouse model in response to 9‐cis retinoic acid (9cRA) and after lymphocyte‐specific genetic targeting of the receptor RARα. RARα overexpression in antigen‐specific B cells promotes differentiation into plasmablasts at the expense of germinal center B ...
Josephine Scholz +6 more
wiley +1 more source
Det smarta hemmets mundanisering
The smart home around 2020 is based on interconnected software-equipped things that through automation are supposed to deliver new pleasures and conveniences. This technological makeover of domestic settings is characterised by consumption of things that
Robert Willim
doaj +1 more source
Abstract Version management is a prerequisite for digital information flow between phases in the planning and building processes. Information evolves over time and many parties retrieve information from the various phases. The aim of this article is to evaluate versioning methods, focusing on geodata buildings in the 3D cadastre process.
Helen Eriksson +3 more
wiley +1 more source
Interpreting the Smartphone Life Cycle Through Smarta
Many complex systems, such as the product life cycle (PLC), can be described in terms of networks, with elements interacting and based on terms of graph theory.
Kristian Alonso-Stenberg +3 more
doaj +1 more source
Smarta tips och rörliga problem
This article focuses on how smartness relates to transformation and to the defining and solving of problems, by analysing how smartness is practiced and spread in and through practical tips for problematic situations in everyday life.
Ann-Helen Sund
doaj +1 more source
I vårt samhälle läggs stor vikt vid att vi ska kunna säga farväl till våra nära och kära när de ligger för döden. Covid-19-pandemin har inte bara orsakat ett stort antal dödsfall utan också medfört hinder för anhörigas möjligheter att närvara i ...
Cathrin Wasshede, Sofia Björk
doaj +1 more source
What are the (cultural) meanings of pain? From the perspective of individual life stories, chronic pain may be analysed as a common idiom for communicating personal and interpersonal problems.
Billy Ehn
doaj +1 more source

