Results 71 to 80 of about 3,067,929 (312)
Discovery Prospects of a Light Scalar in the NMSSM
, 2016 We study a region in the NMSSM parameter space in which the mass of the SM-like Higgs boson is uplifted by ~4-17 GeV, allowing for stop masses and |A_t| A -> Z + H_S.
Ellwanger, Ulrich +1 more
core +1 more source
Fetal Brain Tumor Harboring a Unique ROCK1::BRAF Fusion
Pediatric Blood &Cancer, EarlyView.
Marllon Cindra Sant'Ana +8 more
wiley +1 more source
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
, 2011 We describe a method to couple Z' gauge bosons to the standard model (SM), without charging the SM fields under the U(1)', but instead through effective higher dimension operators.
Fox, Patrick J. +3 more
core +1 more source
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Nuclear PTEN safeguards pre-mRNA splicing to link Golgi apparatus for its tumor suppressive role
Nature Communications, 2018 Cytoplasmic PTEN is a tumor suppressor that antagonises PI3K signalling. Here, the authors show that nuclear PTEN can interact with the spliceosomal proteins and drive pre-mRNA splicing in a phosphatase-independent manner, in particular, PTEN depletion ...
Shao-Ming Shen +13 more
doaj +1 more source
Aktualności Neurologiczne, 2015 Stwardnienie rozsiane to zapalno-demielinizacyjna choroba ośrodkowego układu nerwowego, w której patogenezie istotną rolę odgrywają zaburzenia odpowiedzi immunologicznej komórkowej i humoralnej.
Maciej Maciejowski
doaj +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
The Spectrum of the 4-Generation Dirac-Kaehler Extension of the SM
, 2010 We compute the mass spectrum of the fermionic sector of the Dirac-Kaehler extension of the SM (DK-SM) by showing that there exists a Bogoliubov transformation that transforms the DK-SM into a flavor U(4) extension of the SM (SM-4) with a particular ...
Abbas +20 more
core +1 more source
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source