Results 71 to 80 of about 508,944 (247)
Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes
FEBS Open Bio, EarlyView.Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard +12 more
wiley +1 more source
FEBS Open Bio, EarlyView.The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley +1 more source
The Canadian Entomologist, 1904 ♀ and ♂ new to Vancouver. Hitherto only the male of this fossorial wasp had been known. The males recorded in the literature came from Nove Scotia, Cananda; Montana, Colorado, Arizona, Oregon and Washington. The female is related to T. medius, Fox, but differs in size, sculpture and ornamentation, particularly in the contrast between the deep median ...
openaire +2 more sources
Pathways and pitfalls: a qualitative study of student experiences in biomedical science education
FEBS Open Bio, EarlyView.Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell +8 more
wiley +1 more source
Binary Estimator Selection Methods for Hearing Aids With a Remote Microphone
IEEE AccessUsing a high signal-to-noise ratio remote microphone (RM) with hearing aids (HAs) is advantageous for HA users. However, the benefit depends significantly on the properties of the wireless channel.
Vasudha Sathyapriyan +5 more
doaj +1 more source
FEBS Open Bio, EarlyView.Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty +13 more
wiley +1 more source
Aging Is a Key Driver for Adult Acute Myeloid Leukemia
Aging and Cancer, EarlyView.Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley +1 more source
Developmental and Epileptic Encephalopathy due to Biallelic Pathogenic Variants in PIGM
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective PIGM encodes a critical enzyme in the glycosylphosphatidylinositol (GPI)‐anchor biosynthesis pathway. While promoter‐region mutations in PIGM have been associated with a relatively mild phenotype characterized by portal vein thrombosis and absence seizures, recent evidence suggests that coding‐region mutations result in a more severe
Júlia Sala‐Coromina +11 more
wiley +1 more source
Um Olhar Sobre o Centro Apoio Alzheimer Viseu
Millenium, 2017 Introdução: Em todo o mundo é diagnosticado um novo caso de demência a cada 3 segundos, perfazendo cerca de 9,9 milhões de novos casos em 2015 (Prince, et al., 2015).
José Carreira +2 more
doaj
River interlinking and biodiversity risks in Indian freshwater ecosystems
Scientific ReportsIndia’s National River Linking Project (NRLP) is a large-scale inter-basin water transfer scheme designed to address water scarcity and excesses by connecting surplus basins to deficit ones across the country.
Aravind Neelavar Ananthram +3 more
doaj +1 more source