Results 271 to 280 of about 118,693 (302)

Intracellular Signaling of the TGF‐β Superfamily by Smad Proteins

Annals of the New York Academy of Sciences, 1999
Abstract: TGF‐β is a potent inhibitor of cell growth, and accumulating evidence suggests that perturbation of the TGF‐β signaling pathway leads to tumorigenesis. Smads are recently identified proteins that mediate intracellular signaling of the TGF‐β superfamily. Smads 2 and 3 are phosphorylated by the TGF‐β type I receptor.
M, Kawabata, T, Imamura, H, Inoue, J, Hanai, A, Nishihara, A, Hanyu, M, Takase, Y, Ishidou, Y, Udagawa, E, Oeda, D, Goto, K, Yagi, M, Kato, K, Miyazono   +13 more
openaire   +2 more sources

Smad Proteins in Apoptotic and Survival Signaling

2007
Perhaps the most critical decision to be made during the life of a cell is whether to live or to die. Signaling events initiated by TGF-β superfamily cytokines play a critical role in specifying cell death and survival responses. Of particular importance in this signaling process are the Smad proteins.
Andrew R. Conery, Kunxin Luo
openaire   +1 more source

Phosphorylation of Smad Signaling Proteins by Receptor Serine/Threonine Kinases

2003
Transforming growth factor-β (TGF-β) family members, which include TGF-βs, activins, and bone morphogenetic proteins (BMPs), elicit their multifunctional effects by binding to and complex formation ...
S, Souchelnytskyi, L, Rönnstrand, C H, Heldin, P, ten Dijke   +3 more
openaire   +2 more sources

Creatine promotes cancer metastasis through activation of Smad2/3

Cell Metabolism, 2021
Fei Zhang, David S Hsu, Pu Gao
exaly  

Smad Proteins in TGFβ Signaling

2006
Sylviane Dennler, Peter Dijke
openaire   +1 more source

Identification of a TGF-β/SMAD/lnc-UTGF positive feedback loop and its role in hepatoma metastasis

Signal Transduction and Targeted Therapy, 2021
Bin-kui Li, Jian-hong Fang, Shi-Mei Zhuang   +2 more
exaly  

Smad Interactors in Bone Morphogenetic Protein Signaling

2003
X, Yang, X, Cao
openaire   +2 more sources

Carboxy-terminally truncated Gli3 proteins associate with Smads

Nature Genetics, 1998
Liu, F, Massagué, J, Ruiz Altaba, Ariel
openaire   +3 more sources

Nucleocytoplasmic Shuttling of Smad Proteins

2007
Bernhard Schmierer, Caroline S. Hill
openaire   +1 more source

Smad-dependent and Smad-independent pathways in TGF-β family signalling

Nature, 2003
Ying E Zhang
exaly