Results 71 to 80 of about 1,984,822 (289)

Small Area Estimation under Poisson–Dirichlet Process Mixture Models

open access: yesAxioms
In this paper, we propose an improved Nested Error Regression model in which the random effects for each area are given a prior distribution using the Poisson–Dirichlet Process. Based on this model, we mainly investigate the construction of the parameter
Xiang Qiu   +3 more
doaj   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Simulation Tools for Small Area Estimation: Introducing the R-package saeSim

open access: yesAustrian Journal of Statistics, 2016
The demand for reliable regional estimates from sample surveys has been substantially grown over the last decades. Small area estimation provides statistical methods to produce reliable predictions when the sample sizes in regions are too small to apply ...
Sebastian Warnholz, Timo Schmid
doaj   +1 more source

New important developments in small area estimation

open access: yes, 2010
The purpose of this paper is to review and discuss some of the new important developments in small area estimation (SAE) methods. Rao (2003) wrote a very comprehensive book, which covers all the main developments in this topic until that time and so the ...
Pfeffermann, Danny
core  

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

open access: yesMolecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg   +43 more
wiley   +1 more source

Small area estimation on poverty indicators [PDF]

open access: yes
We propose to estimate non-linear small area population quantities by using Empirical Best (EB) estimators based on a nested error model. EB estimators are obtained by Monte Carlo approximation.
Isabel Molina, J.N.K. Rao
core  

Small area estimation for spatially correlated populations - a comparison of direct and indirect model-based methods [PDF]

open access: yes, 2007
Linear mixed models underpin many small area estimation (SAE) methods. In this paper we investigate SAE based on linear models with spatially correlated small area effects where the neighbourhood structure is described by a contiguity matrix. Such models
Chambers, Ray   +2 more
core   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

open access: yesMolecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix   +13 more
wiley   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung   +17 more
wiley   +1 more source

Improving small area estimation by combining surveys: new perspectives in regional statistics [PDF]

open access: yes
A national survey designed for estimating a specific population quantity is sometimes used for estimation of this quantity also for a small area, such as a province.
Albert Satorra, Alex Costa, Eva Ventura
core  

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