Results 181 to 190 of about 12,783,707 (261)

AI‐Powered Framework for Evaluating Drug Efficacy for Three‐Dimensional In Vitro Cancer Models in Robot‐Assisted Production

Advanced Robotics Research, EarlyView.
An AI‐powered, robot‐assisted framework automatically produces, images, and analyzes 3D tumor spheroids to evaluate drug efficacy. Integrated modules handle spheroid formation, live/dead staining, brightfield imaging, and automated image analysis, including spheroid segmentation, viability and metrics to assess the drug treatment efficacy. The workflow
Dalia Mahdy, Jesus Nieves, Lukas Königer, Matthias Peindl, Fabio Erhard, Marc Möllmann, Anke Klingner, Markus Münig, Bibin Babu, Thomas Schwarz, Marco Metzger, Gudrun Dandekar, Maximiliane Wußmann, Jan Hansmann   +13 more
wiley   +1 more source

Paraneoplastic neurological syndromes of small cell lung cancer

Advances in Psychiatry and Neurology
Maedeh Barahman, Gholamreza Shamsaei, Davood Kashipazha, Mohammad Bahadoram, Esma’il Akade   +4 more
doaj   +1 more source

Multilevel Network Meta-Regression With a Survival Outcome and an Application to Non-Small Cell Lung Cancer. [PDF]

Stat Med
Jia R, Yi H, Teng Z, Tang S, Wang J, Ma S.   +5 more
europepmc   +1 more source

Cross‐Scale Hierarchical Targeted Delivery System Based on Small‐Scale Magnetic Robots

Advanced Robotics Research, EarlyView.
This article reviews a cross‐scale hierarchical targeted delivery system that integrates magnetic continuum robots and magnetic microrobots. By combining rapid long‐range navigation with precise microscale targeting, the system overcomes key limitations of single‐scale approaches.
Junjian Zhou, Zhiqiang Chen, Yuanbiao Ma, Zhiqiang Tang, Qianqian Wang   +4 more
wiley   +1 more source

Advanced non-small cell lung cancer with SMARCA4 deficiency: a case report. [PDF]

Front Oncol
Chai J, Gong Y, Gong L, Wang L, Deng X, Luo Z, Xiong J, Luo M.   +7 more
europepmc   +1 more source

Coixenolide Enhances Antitumor Immunity of Cytotoxic CD8+ T Cells by Inhibiting S100A8/A9‐CD36 Axis in Obesity‐Associated Pancreatic Adenocarcinoma

Advanced Science, EarlyView.
Pancreatic adenocarcinoma (PAAD) remains highly lethal with limited treatment options. This study demonstrates that coixenolide, a bioactive compound from Coix lacryma‐jobi L. and a key component of the clinically approved Kanglaite injection, exhibits enhanced antitumor efficacy in high‐fat diet (HFD)‐induced obese mice bearing PAAD tumors compared to
Kaidi Chen, Rong Chen, Wei Li, Bin Song, Ruiying Zhang, Lewei Dai, Yuwei Qi, Ruqian Chen, Yifan Xu, Hangbin Li, Jingyi Huang, Fangping Wu, Jianan Peng, Xinyu Wang, Yang Xiong, Chaofeng Mu, Guilin Cheng, Zhaoshen Li, Shanming Ruan, Lei Huang, Mancang Gu   +20 more
wiley   +1 more source

Current status and future of immunotherapy in non-small cell lung cancer

Around 85% of lung cancer cases are non-small cell lung cancer (NSCLC). Recent treatment used for NSCLC has been changed to immunotherapy, especially immune checkpoint inhibitors (ICIs), such as PD-1/PD-L1 and CTLA-4 inhibitors. These treatments increase
Tsai, Ping Lien
core  

Cancer Vaccine Strategies in Non-Small Cell Lung Cancer. [PDF]

Vaccines (Basel)
Velasco RN, Thamaraiselvan P, Garbo E, Novello S, Passiglia F.   +4 more
europepmc   +1 more source

Modulation of miR‐23b Wnt/β‐catenin Axis Strengthens Endothelial Barrier Properties

Advanced Science, EarlyView.
Early blood‐brain barrier (BBB) disruption contributes to stroke and CNS disease pathology. miR‐23b was identified as a regulator of BBB integrity in brain endothelial cells. Inhibition of miR‐23b enhanced barrier‐associated properties, promoted repair‐related signaling, and reduced BBB leakage in experimental stroke models, supporting further ...
Victor Anthony Martinez, Rose E. Presby, Sara Nakanishi, Pallavi Gaur, Ugur Akcan, Johannes Daugaard Krog, Iben Daugaard Krog, Lipi Das, David S. Johnson, Danny Jamoul, Douglas Jury, Brian Lawson, Jacob Körbelin, Lewis M. Brown, Vilas Menon, Dritan Agalliu, Irene Munk Pedersen   +16 more
wiley   +1 more source

SCLC TumorMiner: A genomics platform for small cell lung cancer precision oncology. [PDF]

iScience
Elloumi F, Dhall A, Taniyama D, Luna A, Arakawa Y, Varma S, Wang Y, Tehim A, Raffeld M, Aldape K, Redon C, Shrestha R, Reinhold W, Aladjem M, Del Rivero J, Roper N, Thomas A, Pommier Y.   +17 more
europepmc   +1 more source