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Cytokeratin-negative small cell lung carcinoma
Rare Tumors, 2011 Cytokeratins (CK) are good markers of epithelial tumors, and most of carcinomas including small cell lung carcinoma (SCLC) expresses CK. Herein reported is a case of SCLC without CK expression.
Tadashi Terada
doaj +3 more sources
Chromothripsis-Mediated Small Cell Lung Carcinoma. [PDF]
Cancer DiscovAbstract Small cell lung carcinoma (SCLC) is a highly aggressive malignancy that is typically associated with tobacco exposure and inactivation of RB1 and TP53 genes. Here, we performed detailed clinicopathologic, genomic, and transcriptomic profiling of an atypical subset of SCLC that lacked RB1 and TP53 co-inactivation and arose in ...
Rekhtman N +41 more
europepmc +3 more sources
Small cell carcinoma of the lung [PDF]
Postgraduate Medical Journal, 1980 Summary Over a 5-year period 230 cases of small cell carcinoma presented to Brompton Hospital, London. The male to female ratio was 2.5:1 and 39% had evidence of extrathoracic disease. Forty-five patients were untreated and had a median survival of 70 days.
J A, Meyer, F B, Parker
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World Journal of Surgical Oncology, 2022 Purpose Current research has shown a link between ABO blood group and many diseases. The purpose of this study aimed to investigate the influence of the ABO blood group on the risk of developing different pathological types of lung cancer.
Haotian Yang +8 more
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The Expression of miR-375 Is Associated with Carcinogenesis in Three Subtypes of Lung Cancer. [PDF]
PLoS ONE, 2015 Many studies demonstrated unique microRNA profiles in lung cancer. Nonetheless, the role and related signal pathways of miR-375 in lung cancer are largely unknown. Our study investigated relationships between carcinogenesis and miR-375 in adenocarcinoma,
Yi Jin +12 more
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Partial Response in an RRx-001-Primed Patient with Refractory Small-Cell Lung Cancer after a Third Introduction of Platinum Doublets. [PDF]
, 2016 Small-cell lung cancer (SCLC), initially exquisitely sensitive to first-line cisplatin/etoposide, invariably relapses and acquires a multidrug chemoresistant phenotype that generally renders retreatment with first-line therapy both futile and ...
Brzezniak, Christina +7 more
core +6 more sources
Thoracic Cancer, 2021 Immune checkpoint inhibitors with chemotherapy have been shown to exhibit remarkable efficacy for advanced non‐small‐cell lung carcinoma and are under investigation as an induction therapy.
Shunichi Saito +6 more
doaj +1 more source
Changing trends in incidence of lung cancer by histological type in Montenegro [PDF]
Srpski Arhiv za Celokupno Lekarstvo, 2014 Introduction. Lung cancer is one of the most common malignant neoplasms, as well as the most common cause of death cancer. Most lung cancers are squamous cell carcinomas, small cell carcinomas or adenocarcinomas. Objective.
Medenica Milić +4 more
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Lung Cancer: A Literature Review
Jurnal Respirasi, 2023 Lung cancer is a cancer whose onset starts in the lungs where there is an abnormal cell growth that is very fast and uncontrolled. The abnormal cell growth is triggered by deoxyribonucleic acid (DNA) damage, including deletions in the DNA section ...
Yan Efrata Sembiring +8 more
doaj +1 more source
International lung cancer trends by histologic type: male:female differences diminishing and adenocarcinoma rates rising. [PDF]
, 2005 Lung cancer rates have peaked among men in many areas of the world, but rates among women continue to rise. Most lung cancers are squamous cell carcinoma, small cell carcinoma, or adenocarcinoma; trends vary according to type.
Bray, Freddie +3 more
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