Results 131 to 140 of about 10,585,232 (232)
Novel and emerging skin carcinomas and adnexal tumours
Histopathology, EarlyView.The present review aims to provide an overview of the main emerging skin epithelial tumours, with particular emphasis on salivary gland analogue sweat gland tumours and poorly differentiated carcinomas. Epidermal and adnexal tumours of the skin constitute a complex and heterogeneous group of neoplasms, with distinct morphology and behaviour.
Thibault Kervarrec +2 more
wiley +1 more source
Histopathology, EarlyView.Whole‐slide analysis of melanoma identified higher‐proliferation mitotic hotspots than routine pathology assessment and revealed distinct spatial patterns of mitotic organization, highlighting the potential of computational mitosis mapping to provide insights beyond conventional mitotic counting.
Shlomo Tsuriel +4 more
wiley +1 more source
Novel and emerging cutaneous soft tissue tumours
Histopathology, EarlyView.This review outlines the defining histopathological, immunophenotypic and molecular features of novel and emerging cutaneous soft tissue tumours, including hybrid superficial ALK‐rearranged myxoid spindle cell neoplasm/epithelioid fibrous histiocytoma, superficial neurocristic tumour, ALK‐rearranged epithelioid vascular neoplasm and MITF pathway ...
Saba Shafi, Josephine K Dermawan
wiley +1 more source
Distinct Rb expression pattern in HPV‐associated neuroendocrine carcinomas of the uterine cervix
Histopathology, EarlyView.Most uterine cervical neuroendocrine carcinoma (UCNEC) cases are HPV‐associated and are characterized by partial loss of Rb, p16 overexpression, and cyclin D1 negativity. A minority of UCNECs exhibit a distinct pattern, characterized by HPV negativity, retained Rb expression, focal p16 expression and cyclin D1 positivity.
Nobuko Yasutake +12 more
wiley +1 more source
Interleukin‐12: Central Roles in Immune Regulation and Disease Therapy
Immunology &Cell Biology, EarlyView.IL‐12 levels are tightly regulated to balance effective protective immunity against infections and cancer with the risk of excessive inflammation and autoimmune disease. Both insufficient and excessive IL‐12 activity can therefore be detrimental, highlighting the importance of precisely controlling its production and signaling. ABSTRACT Interleukin‐12 (
Anthi Psoma, Geert van den Bogaart
wiley +1 more source
Renal small cell neuroendocrine carcinoma: a case report and literature review. [PDF]
Int J Surg Case RepWei C, Wang X, Shayiremu D, Ren C.
europepmc +1 more source
Periodontal Medicine Rewired: Mechanisms Linking Periodontitis to Systemic Diseases
Journal of Periodontal Research, EarlyView.This review reorganizes decades of research in periodontal medicine into a multi‐dimensional framework, illustrating how periodontitis influences systemic health through at least seven interconnected mechanisms. ABSTRACT Periodontitis is now recognized not merely as a localized oral condition but as a systemic disease linked to over 70 communicable and
Mario Romandini +3 more
wiley +1 more source
Primary small-cell neuroendocrine carcinoma of the bladder: a very rare histological subtype. [PDF]
Oxf Med Case ReportsMesmoudi S +10 more
europepmc +1 more source
Understanding extracellular vesicles in antiaging
Periodontology 2000, EarlyView.Abstract Background Aging is a multifactorial process marked by gradual cellular dysregulation, regulated by hallmarks, including genomic instability, mitochondrial dysregulation, and chronic inflammation. Extracellular vesicles (EVs), especially exosomes, have emerged as pivotal mediators of cell‐to‐cell communication with potential roles in both ...
Paras Ahmad +3 more
wiley +1 more source
Sarcomatoid Large Cell Neuroendocrine Carcinoma of the Kidney A Case Report
, 2017 BACKGROUND: Neuroendocrine tumors of the kidney may develop within the renal parenchyma or may arise from the pelvic urothelial mucosa.
Ogut, Betul +4 more
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