Results 161 to 170 of about 352,358 (326)

Post-transcriptional suppression of gene expression in Xenopus embryos by small interfering RNA [PDF]

, 2002
Ye Zhou
openalex   +1 more source

MagPiezo: A Magnetogenetic Platform for Remote Activation of Endogenous Piezo1 Channels in Endothelial Cells

Advanced Functional Materials, EarlyView.
MagPiezo enables wireless activation of endogenous Piezo1 channels without genetic modification using 19 nm magnetic nanoparticles and low‐intensity magnetic fields. It generates torque forces at the piconewton scale to trigger mechanotransduction in endothelial cells, standing as a novel platform to interrogate and manipulate Piezo1 activity in vitro.
Susel Del Sol‐Fernández, Mariarosaria De Simone, Yilian Fernández‐Afonso, Daniel Garcia‐Gonzalez, Pablo Martínez‐Vicente, Thomas van Zanten, Raluca M. Fratila, Maria Moros   +7 more
wiley   +1 more source

Immunoinformatic and molecular docking approaches: siRNA prediction to silence cell surface binding protein of monkeypox virus

Beni-Suef University Journal of Basic and Applied Sciences
Background Monkeypox virus (MPV), an endemic pathogen in Africa, shares clinical similarities with smallpox. Recent reports indicate a concerning increase in the number of MPV cases detected outside its endemic region, highlighting the emergence of a ...
Rahatul Islam, Asif Shahriar, Muhammad Ramiz Uddin, Nour Fatema   +3 more
doaj   +1 more source

Apoptosis of Canine Mammary Tumor Cells Induced by Small Interfering RNA (siRNA) against Bcl-xL Gene

, 2006
Fumito Tsuchiya, Rui Kano, Junichi Sano, K. Oguma, Atsuhiko Hasegawa   +4 more
openalex   +2 more sources

Data from Small Interfering RNA–Directed Knockdown of Uracil DNA Glycosylase Induces Apoptosis and Sensitizes Human Prostate Cancer Cells to Genotoxic Stress

, 2023
Sai Murali Krishna Pulukuri, James A. Knost, Norman Estes, Jasti S. Rao   +3 more
openalex   +1 more source

Poly(lactic‐co‐glycolic acid) Nanoparticles for IL‐12 Self‐Amplifying RNA Delivery in Glioblastoma Models

Advanced Functional Materials, EarlyView.
xxxx. ABSTRACT Glioblastoma (GBM) remains one of the most lethal brain cancers, with median survival rarely exceeding 15 months after diagnosis. Interleukin‐12 (IL‐12) is a potent immunostimulatory cytokine capable of reshaping the tumor microenvironment (TME), yet its clinical translation is hindered by systemic toxicity and short half‐life. RNA‐based
Fatima Hameedat, Johan Sebastian Lopez‐Parra, Willem M. H. Hoogaars, Emma Dijkstra, Cynthia Huang, Irafasha C. Casmil, Anna K. Blakney, Peter Olinga, Barbara Rothen‐Rutishauser, Hélder A. Santos, Alke Petri‐Fink, Flávia Sousa   +11 more
wiley   +1 more source

A Lipid-Coated Nanoconstruct Composed of Gold Nanoparticles Noncovalently Coated with Small Interfering RNA: Preparation, Purification and Characterization [PDF]

, 2021
Anna V. Epanchintseva, Julia Poletaeva, Ilya S. Dovydenko, Boris P. Chelobanov, Д. В. Пышный, E. I. Ryabchikova, I. A. Pyshnaya   +6 more
openalex   +1 more source

Gene Silencing With Small Interfering RNA

Liver Transplantation, 2019
RNA interference (RNAi) is a natural process of posttranscriptional gene regulation that has raised a lot of attention culminating with the Nobel Prize in Medicine in 2006. RNAi-based therapeutics have been tested in experimental transplantation to reduce ischemia/reperfusion injury (IRI) with success.
Thijssen, Max F., Bruggenwirth, Isabel M. A., Gillooly, Andrew, Khvorova, Anastasia, Kowalik, Timothy F., Martins, Paulo N.   +5 more
openaire   +1 more source

Membrane Fusion‐Inspired Nanomaterials: Emerging Strategies for Infectious Disease and Cancer Diagnostics

Advanced Healthcare Materials, EarlyView.
Membrane fusion‐inspired nanomaterials offer transformative potential in diagnostics by mimicking natural fusion processes to achieve highly sensitive and specific detection of disease biomarkers. This review highlights recent advancements in nanomaterial functionalization strategies, signal amplification systems, and stimuli‐responsive fusion designs,
Sojeong Lee, Khulan Nyamzaya, Jueun Han, Yejin Song, Jihee Lee, Jung Hyun Jo, Seungmin Bang, Eun‐Kyung Lim, Seungjoo Haam, Eunjung Kim   +9 more
wiley   +1 more source

Updates in Small Interfering RNA for the Treatment of Dyslipidemias. [PDF]

Curr Atheroscler Rep, 2023
Carugo S, Sirtori CR, Gelpi G, Corsini A, Tokgozoglu L, Ruscica M.   +5 more
europepmc   +1 more source