Results 161 to 170 of about 625,167 (353)

Small interfering RNA for cancer treatment: overcoming hurdles in delivery

Acta Pharmaceutica Sinica B, 2020
N. Charbe, Nikhil D. Amnerkar, B. Ramesh, M. Tambuwala, H. Bakshi, Alaa A. A. Aljabali, S. Khadse, R. Satheeshkumar, S. Satija, S. Satija, Meenu Metha, Meenu Metha, D. Chellappan, G. Shrivastava, G. Gupta, P. Negi, K. Dua, K. Dua, Flavia C. Zacconi   +18 more
semanticscholar   +1 more source

Ischemic Myocardium Targeting Peptide‐Guided Nanobubbles for Multimodal Imaging and Treatment of Coronary Microvascular Dysfunction

Advanced Healthcare Materials, EarlyView.
Nanobubbles functionalized with indocyanine green and ischemic myocardium‐targeting peptide effectively target cardiomyocytes and enable the multimodal (fluorescence, ultrasonic, and photoacoustic) imaging of ischemic myocardium in mice with coronary microvascular dysfunction (CMD).
Bo Yu, Ziwei Pang, Jing Zhao, Jingyi Xue, Hsuan Lo, Tiancheng Gu, Ping Zhang, Jiawei Tian, Guo‐Qing Du   +8 more
wiley   +1 more source

Small interfering RNA-mediated allele-selective silencing of von Willebrand factor in vitro and in vivo. [PDF]

Blood Adv, 2023
Jongejan YK, Schrader Echeverri E, Dirven RJ, Paunovska K, Linthorst NA, de Jong A, Wellershoff JC, van der Gouw KD, van Vlijmen BJM, Dahlman JE, Eikenboom JCJ.   +10 more
europepmc   +1 more source

49. Modulation of Gene Expression by Lentiviral-Mediated Delivery of Small Interfering RNA [PDF]

, 2003

openalex   +1 more source

Recent Applications of Mesoporous Silica Nanoparticles in Gene Therapy

Advanced Healthcare Materials, EarlyView.
The review summarizes the synthesis of mesoporous silica nanoparticles (MSNs) with modifiable surface properties, functionalization strategies, mechanism of therapeutic payload release, and current applications in gene therapy, focusing on their capabilities in the targeted delivery of therapeutic nucleic acids, CRISPR‐Cas systems, and other genetic ...
Tamanna Binte Huq, Punnya Anil Kumar Jeeja, Sudip Kumar Dam, Sabya Sachi Das, Juan L. Vivero‐Escoto   +4 more
wiley   +1 more source

Inhibition of intracellular hepatitis C virus replication by synthetic and vector‐derived small interfering RNAs [PDF]

, 2003
Takanori Yokota, Naoya Sakamoto, Nobuyuki Enomoto, Yoko Tanabe, Makoto Miyagishi, Shinya Maekawa, Li Yi, Masayuki Kurosaki, Kazunari Taira, Mamoru Watanabe, Hidehiro Mizusawa   +10 more
openalex   +1 more source

Harnessing Nanohybridized Niclosamide for Precision Mpox Therapeutics

Advanced Healthcare Materials, EarlyView.
This study investigates the potential of nanohybridized niclosamide as a therapeutic agent for Mpox, focusing on enhanced bioavailability, improved antiviral efficacy, and controlled drug release achieved through nanoengineering. The research emphasizes significant advancements in formulation strategies, mechanistic insights, and therapeutic outcomes ...
N. Sanoj Rejinold, Geun‐woo Jin, Jin‐Ho Choy   +2 more
wiley   +1 more source

Median and Small Parsimony Problems on RNA trees [PDF]

arXiv
Motivation: Non-coding RNAs (ncRNAs) express their functions by adopting molecular structures. Specifically, RNA secondary structures serve as a relatively stable intermediate step before tertiary structures, offering a reliable signature of molecular function.
arxiv  

A Wireless Cortical Surface Implant for Diagnosing and Alleviating Parkinson's Disease Symptoms in Freely Moving Animals

Advanced Healthcare Materials, EarlyView.
A wireless cortical surface implant employing graphene electrode arrays diagnoses and alleviates Parkinson's disease symptoms in freely moving animals. The device continuously monitors cortical activity and delivers targeted stimulation, restoring beta–gamma and delta oscillations.
Hongseong Shin, Kyungtae Kim, Jaeseung Lee, Johyeon Nam, Eunha Baeg, Chaeyeon You, Hanseul Choi, Minji Kim, Chun Kee Chung, Jae Geun Kim, Jong Hyun Ahn, Miryung Han, Jibum Kim, Sungchil Yang, Sung Q Lee, Sunggu Yang   +15 more
wiley   +1 more source

Inclisiran-Safety and Effectiveness of Small Interfering RNA in Inhibition of PCSK-9. [PDF]

Pharmaceutics, 2023
Wołowiec Ł, Osiak J, Wołowiec A, Wijata A, Grześk E, Kozakiewicz M, Banach J, Nowaczyk A, Nowaczyk J, Grześk G.   +9 more
europepmc   +1 more source