Results 181 to 190 of about 625,167 (353)

Correction for Song et al., "Sustained Small Interfering RNA-Mediated Human Immunodeficiency Virus Type 1 Inhibition in Primary Macrophages". [PDF]

J Virol, 2023
Song E, Lee S-K, Dykxhoorn DM, Novina C, Zhang D, Crawford K, Cerny J, Sharp PA, Lieberman J, Manjunath N, Shankar P.   +10 more
europepmc   +1 more source

Faculty Opinions recommendation of RNA interference in Trypanosoma brucei: cloning of small interfering RNAs provides evidence for retroposon-derived 24-26-nucleotide RNAs.

, 2001
Marilyn Parsons
openalex   +2 more sources

Specific HIV-1 env gene silencing by small interfering RNAs in human peripheral blood mononuclear cells [PDF]

, 2003
W-S Park, Masaaki Hayafune, Naoko Miyano‐Kurosaki, Hiroaki Takaku   +3 more
openalex   +1 more source

Rational Design of Metal–Organic Frameworks for Pancreatic Cancer Therapy: from Machine Learning Screening to In Vivo Efficacy

Advanced Materials, EarlyView.
This work explores the MOF landscape to select a single, optimal candidate for successfully delivering cancer drugs (gemcitabine, paclitaxel, SN‐38) into tough pancreatic tumors. Machine learning and simulations guide this search, demonstrating colloidal stability, excellent biocompatibility, cellular uptake, and sustained release.
Francesca Melle, Dhruv Menon, João Conniot, Jon Ostolaza‐Paraiso, Sergio Mercado, Jhenifer Oliveira, Xu Chen, Bárbara B. Mendes, João Conde, David Fairen‐Jimenez   +9 more
wiley   +1 more source

Porous silicon nanotube bundles as nanocarriers for small interfering RNA delivery

Nano Select
We describe in this work an evaluation of bundles of hollow mesoporous silicon nanotubes to facilitate transfection of HeLa cells using small interfering RNA designed to knock down expression of Enhanced Green Fluorescent Protein (eGFP).
Nguyen T. Le, Giridhar R. Akkaraju, Jeffery L. Coffer   +2 more
doaj   +1 more source

Comparison of different antisense strategies in mammalian cells using locked nucleic acids, 2'-O-methyl RNA, phosphorothioates and small interfering RNA [PDF]

, 2003
Arnold Grünweller, Eliza Wyszko, Birgit Bieber, Ricarda Jahnel, Volker A. Erdmann, Jens Kurreck   +5 more
openalex   +1 more source

RiNALMo: General-Purpose RNA Language Models Can Generalize Well on Structure Prediction Tasks [PDF]

arXiv
While RNA has recently been recognized as an interesting small-molecule drug target, many challenges remain to be addressed before we take full advantage of it. This emphasizes the necessity to improve our understanding of its structures and functions. Over the years, sequencing technologies have produced an enormous amount of unlabeled RNA data, which
arxiv  

Small Interfering RNA-Induced Transcriptional Gene Silencing in Human Cells

Science, 2004

semanticscholar   +1 more source

Protein‐Like Polymers Targeting Keap1/Nrf2 as Therapeutics for Myocardial Infarction

Advanced Materials, EarlyView.
We describe a Keap1 targeting protein‐like polymer (PLP) which activates Nrf2, an important cytoprotective transcription factor for relieving myocardial infarction‐induced oxidative stress. This PLP increases cell survival in vitro in multiple relevant cardiac cell types and elicits pro‐reparative responses, improving cardiac function in a preclinical ...
Joshua M. Mesfin, Kendal P. Carrow, Alexander Chen, Madeline P. Hopps, JoJo J. Holm, Quincy P. Lyons, Michael B. Nguyen, Jervaughn D. Hunter, Assa Magassa, Elyse G. Wong, Kate Reimold, Sriya N. Paleti, Emily Gardner, Matthew P. Thompson, Colin G. Luo, Xiaoyu Zhang, Karen L. Christman, Nathan C. Gianneschi   +17 more
wiley   +1 more source

[Retracted] Inhibiting proliferation and migration of lung cancer using small interfering RNA targeting on Aldo‑keto reductase family 1 member B10. [PDF]

Mol Med Rep, 2023
Zhou Z, Zhao Y, Gu L, Niu X, Lu S.
europepmc   +1 more source