Results 51 to 60 of about 689,619 (309)
FEBS Letters, EarlyView.Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi +5 more
wiley +1 more source
Cellular and Molecular Gastroenterology and Hepatology, 2020 Despite growing literature characterizing the fecal microbiome and its association with health and disease, few studies have analyzed the microbiome of the small intestine.
Arthur J. Kastl, Jr. +3 more
doaj +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Na+-H+ exchange activity in brush-border membrane vesicles isolated from chick small intestine [PDF]
, 1995 This study was undertaken to investigate the presence of a Na+{single bond}H+ antiporter in brush-border membrane vesicles (BBMV) isolated from chick small intestine.
Cano Rodríguez, María Mercedes +2 more
core +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Development of Small and Large Intestine
Bezmiâlem Science, 2017 Epithelial components of the organs of the digestive system are derived from endoderm whereas connective tissue and muscle components are derived from mesoderm. At the 3-4th of development, as a result of cephalocaudal and lateral foldings of the embryo,
Mukaddes EŞREFOĞLU, Aslı ÇETİN
doaj +1 more source
Distinct human stem cell populations in small and large intestine [PDF]
, 2015 The intestine is composed of an epithelial layer containing rapidly proliferating cells that mature into two regions, the small and the large intestine. Although previous studies have identified stem cells as the cell-of-origin for intestinal epithelial ...
Cramer, JM +4 more
core +3 more sources
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
КОМПЛЕКСНАЯ КЛИНИКО-ФУНКЦИОНАЛЬНАЯ ОЦЕНКА ТОНКОЙ КИШКИ ПРИ МЕТАБОЛИЧЕСКОМ СИНДРОМЕ
Архивъ внутренней медицины, 2015 Aim: complex investigation of the small intestine functional condition in metabolic syndrome.Materials and methods.120 patients with metabolic syndrome were examined. We used clinical data and complex examination of the small intestine function.
Я. М. Вахрушев +1 more
doaj +1 more source
Asian Pacific Journal of Cancer Biology, 2022 Background: Intussusception refers to telescoping of one intestinal segment and its mesentery into an adjacent intestinal loop. It is a rather frequent entity in infants with an excellent prognosis.
Maisa Hashem Mohammed
doaj +1 more source