Results 71 to 80 of about 8,186,512 (386)

The role of fibroblast growth factors in cell and cancer metabolism

open access: yesFEBS Letters, EarlyView.
Fibroblast growth factor (FGF) signaling regulates crucial signaling cascades that promote cell proliferation, survival, and metabolism. Therefore, FGFs and their receptors are often dysregulated in human diseases, including cancer, to sustain proliferation and rewire metabolism.
Jessica Price, Chiara Francavilla
wiley   +1 more source

КОМПЛЕКСНАЯ КЛИНИКО-ФУНКЦИОНАЛЬНАЯ ОЦЕНКА ТОНКОЙ КИШКИ ПРИ МЕТАБОЛИЧЕСКОМ СИНДРОМЕ

open access: yesАрхивъ внутренней медицины, 2015
Aim: complex investigation of the small intestine functional condition in metabolic syndrome.Materials and methods.120 patients with metabolic syndrome were examined. We used clinical data and complex examination of the small intestine function.
Я. М. Вахрушев   +1 more
doaj   +1 more source

Enhancement of Acylcarnitine Levels in Small Intestine of Abdominal Irradiation Rats Might Relate to Fatty Acid β-Oxidation Pathway Disequilibration

open access: yesDose-Response, 2022
Objective This study aims to analyze the alteration of carnitine profile in the small intestine of abdominal irradiation-induced intestinal injury rats and explore the possible reason for the altered carnitine profile.
Hai-Xiang Liu   +6 more
doaj   +1 more source

A Cre‐dependent lentiviral vector for neuron subtype‐specific expression of large proteins

open access: yesFEBS Letters, EarlyView.
We designed a versatile and modular lentivector comprising a Cre‐dependent switch and self‐cleaving 2A peptide and tested it for co‐expression of GFP and a 2.8 kb gene of interest (GOI) in mouse cortical parvalbumin (PV+) interneurons and midbrain dopamine (TH+) neurons.
Weixuan Xue   +6 more
wiley   +1 more source

Endoscopic Evaluation of the Small Intestine

open access: yesCanadian Journal of Gastroenterology, 2002
Technological achievements in the area of endoscope design and development have resulted in instruments capable of advancing beyond the reach of simple gastroscopes. Such instruments, known as enteroscopes, form the bases of small bowel endoscopy. Recent
Steven J Shields, Jacques van Dam
doaj   +1 more source

Live Intravital Intestine with Blood Flow Visualization in Neonatal Mice Using Two-photon Laser Scanning Microscopy

open access: yesBio-Protocol, 2021
This protocol describes a novel technique to investigate the microcirculation dynamics underlying the pathology in the small intestine of neonatal mice using two-photon laser-scanning microscopy (TPLSM).
Yuhki Koike   +12 more
doaj   +1 more source

Leiomyosarcomas of the small intestine [PDF]

open access: yesCancer, 1979
Small bowel leiomyosarcomas are uncommon but potentially curable tumors often diagnosed at an advanced stage. Twenty such lesions were studied, and 19 of these produced symptoms and signs. Clinical findings included abdominal pain in 17 (85%), rectal bleeding in 8 (40%), anemia in 7 (35%), intraperitoneal perforation in 6 (30%), and abdominal mass in 4
Kenneth B. Deck, Howard Silberman
openaire   +3 more sources

Multi‐omic characterization of consensus molecular subtype 1 (CMS1) colorectal cancer with dampened immune response improves precision medicine

open access: yesMolecular Oncology, EarlyView.
This study highlights the importance of multi‐omic analyses in characterizing colorectal cancers. Indeed, our analysis revealed a rare CMS1 exhibiting dampened immune activation, including reduced PD‐1 expression, moderate CD8+ T‐cell infiltration, and suppressed JAK/STAT pathway.
Livia Concetti   +10 more
wiley   +1 more source

A Novel Cyber Physical System for 3-D Imaging of the Small Intestine In Vivo

open access: yesIEEE Access, 2015
Small intestine is the longest organ in the gastrointestinal tract where much of the digestion and the food absorption take place. Wireless video capsule endoscope (VCE) is the first device taking 2-D pictures from the lesions and the abnormalities in ...
Kaveh Pahlavan   +8 more
doaj   +1 more source

BMP antagonist CHRDL2 enhances the cancer stem‐cell phenotype and increases chemotherapy resistance in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley   +1 more source

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