Results 151 to 160 of about 600,761 (285)

New species in the Elachista praelineata species group (Lepidoptera, Elachistidae, Elachistinae) from East Africa, with identification keys to the Afrotropical species. [PDF]

Zookeys
Sruoga V, Kaila L.
europepmc   +1 more source

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source

Quantum scrambling and DNA based multilayer image encryption with QTRNG and 6D hyperchaotic keys. [PDF]

Sci Rep
Sridharan S, Ts G, Amirtharajan R, Praveenkumar P.   +3 more
europepmc   +1 more source

Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

Molecular Oncology, EarlyView.
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu, Jianlei Zhao, Aaban Asfar Azmi, Avanti Gupte, Jenna Thibodeau, Shuang Liu, Jinli Yang, Guan Wang, Holly Edwards, Lisa A. Polin, Juiwanna Kushner, Sijana H. Dzinic, Kathryn White, Julie Boerner, Maik Hüttemann, Jay Yang, Yue Wang, Jeffrey W. Taub, Yubin Ge   +18 more
wiley   +1 more source

The Underreported Benefits of Surgical Intervention for Chronic Sequelae of Closed Degloving Injuries: A Case Series. [PDF]

Plast Reconstr Surg Glob Open
Uh JH, Keys KA.
europepmc   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

Concept and feasibility of privacy-preserving record linkage of cancer registry data and claims data in Germany: results from the DigiNet study on stage IV non-small cell lung cancer. [PDF]

J Cancer Res Clin Oncol
Kästner A, Hampf C, Naumann P, Fiedler-Lacombe L, Kron A, Spier A, Simic D, Eilers L, Graw A, Bartholomäus S, Stang A, Reil D, Kirschner-Schwabe R, Selig JI, Wulff J, Dröge P, Ruhnke T, Günster C, Nußbaum U, Marschall U, Mohnke J, Hebbelmann A, Lührig U, Rasokat A, Mildenberger V, Stock S, Kron F, Wolf J, Bialke M, Stahl D, van den Berg N, Hoffmann W.   +31 more
europepmc   +1 more source

Keys to inclusion of small-scale producers in dynamic markets - Innovative practice in connecting small-scale producers with dynamic markets [PDF]

, 2008
Berdegué, Julio A., Biénabe, Estelle, Peppelenbos, Lucian   +2 more
core  

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

An efficient image encryption scheme based on Lorenz system and quantum-inspired walks. [PDF]

Sci Rep
Karmany M, Moawad A, Abaza M, Mansour A, Alfalou A.   +4 more
europepmc   +1 more source