Results 81 to 90 of about 63,392 (262)
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Neurotoxicity is a rare, often dose‐limiting adverse effect of methotrexate (MTX) therapy that disproportionally affects Latino children. Factors contributing to the observed disparity are not well understood. This study leveraged admixture mapping to identify genetic regions associated with MTX‐related neurotoxicity susceptibility ...
Rachel D. Harris +24 more
wiley +1 more source
Graph-based vision transformer with sparsity for training on small datasets from scratch
Scientific ReportsVision Transformers (ViTs) have achieved impressive results in large-scale image classification. However, when training from scratch on small datasets, there is still a significant performance gap between ViTs and Convolutional Neural Networks (CNNs ...
Peng Li +4 more
doaj +1 more source
Characterizing a Key Player in Micro, but Not Small, RNA Interference
PLoS Biology, 2006 Translation repression by RNA interference (RNAi) has emerged in recent years as a ubiquitous, powerful, and precise method for the regulation of gene expression, both naturally and experimentally. In this process, a messenger RNA (mRNA), made from a gene and destined to be translated into a protein, is silenced by a molecule of “interfering” RNA ...
openaire +4 more sources
Impact of Metastatic Patterns on Survival and Response to Therapy in Neuroblastoma
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background While the presence of metastases in neuroblastoma (NB) is a well‐established prognostic factor, the clinical significance of dissemination patterns and tumour burden and their impact on response and survival remains poorly understood.
Mariona Morell‐Daniel +15 more
wiley +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background General pediatricians often evaluate hematologic and oncologic presentations before subspecialty consultation, yet the 2025 Accreditation Council for Graduate Medical Education (ACGME) pediatric requirements reduce inpatient pediatric hematology/oncology (PHO) time, raising questions about resident readiness.
Colburn Yu, Rohini Jain
wiley +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Germ cell tumors (GCTs) often arise in the ovaries and testes (extracranial) but can also develop in the brain (intracranial). We examined the relationship of individual, family, and community‐level socioeconomic status (SES) with stage of disease at diagnosis in a cohort of pediatric patients with GCT from Children's Oncology Group
Heydon K. Kaddas +7 more
wiley +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Neurodevelopmental and neurocognitive difficulties are prevalent among individuals with sickle cell disease and warrant prompt identification and support. This Special Report provides an executive summary of standards and recommendations for surveillance, screening, and evaluation for development and cognition across the lifespan developed by ...
Alyssa M. Schlenz +12 more
wiley +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT As part of the European Cooperative Study Group for Paediatric Rare Tumours initiative, we developed standard clinical practice guidelines for ovarian sex cord stromal tumors, based on comprehensive national and international cohort analyses, literature review, and a final expert consensus conference.
Dominik T. Schneider +15 more
wiley +1 more source
Ancel Keys, the Mediterranean Diet, and the Seven Countries Study: A Review
Journal of Cardiovascular Development and DiseaseThe identification of the “Mediterranean Diet” (MD) by Prof. Ancel Keys is described here, alongside its confirmation through the epidemiological study known as “The Seven Countries Study of Cardiovascular Diseases” (SCS). Prof.
Alessandro Menotti, Paolo Emilio Puddu
doaj +1 more source