Results 91 to 100 of about 5,727,217 (300)

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

open access: yesMolecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico   +5 more
wiley   +1 more source

A Newcastle disease outbreak in backyard and free-range poultry in Slovenia

open access: yesFrontiers in Veterinary Science
Newcastle disease (ND) is a highly contagious and economically important viral disease of poultry, caused by virulent strains of Orthoavulavirus javaense (OAVJ).
Zoran Žlabravec   +10 more
doaj   +1 more source

Influence of some environmental parameters on small mammals (Rodentia, Insectivora) in the Central Alps

open access: yesHystrix, the Italian Journal of Mammalogy, 1997
<strong>Abstract</strong> This paper points out the relationships occurring between small mammal populations studied in some areas of the central-Western italian Alpine Arch, and some environmental parameters that characterize the Alpine ...
Barbara Chiarenzi   +2 more
doaj   +1 more source

Small

open access: yes, 2014
A proverbial objective in nanomaterial science is to construct low-dimensional nanoparticle (NP) assemblies with fascinating properties, which have shown great promise in optical, electronic and biomedical applications.
Yue, Hua   +10 more
core   +1 more source

Bridging the gap: a genetically validated avian chorioallantoic membrane platform for investigation of spontaneous circulating tumor cells

open access: yesMolecular Oncology, EarlyView.
We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth   +17 more
wiley   +1 more source

A case study of critical points for the entry and spread of Salmonella Infantis in a broiler farm

open access: yesIrish Veterinary Journal
Salmonella Infantis is a zoonotic pathogen that frequently persists in broiler production systems, posing a risk to food safety and animal health. Understanding its entry and spread in these systems can inform control measures and reduce contamination. A
Bojan Papić   +5 more
doaj   +1 more source

The crystal structure of the Borrelia burgdorferi nicotinamidase BBE22 resolves a long‐standing annotation error

open access: yesFEBS Open Bio, EarlyView.
The crystal structure of Borrelia burgdorferi nicotinamidase (PncA/BBE22) reveals the correct full‐length protein initiated from a non‐canonical AUU start codon. The structure validates previous biochemical findings and resolves a long‐standing annotation error, demonstrating that the truncated database sequence is structurally incompatible with the ...
Kalvis Brangulis
wiley   +1 more source

Himalayan Vultures in Khodpe, far-west Nepal: is there any threat?

open access: yesJournal of Threatened Taxa, 2015
There is evidence that Himalayan Vulture Gyps himalayensis is susceptible to the veterinary drug diclofenac, which is responsible for the decline of other Gyps species across South Asia.
Manoj Kumar Joshi   +3 more
doaj   +1 more source

Small RNA pathways in mammalian oocytes

open access: yesFEBS Open Bio, EarlyView.
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley   +1 more source

Detection of Leishmania spp. in Small Non-Flying Mammals (Didelphimorphia and Rodentia) from Bahia, Northeast Brazil

open access: yes
This study aimed to identify Leishmania species in small non-flying mammals captured in semi-deciduous forest fragments of the Atlantic Forest and pastures in the Southwest region of Bahia state, Northeast Brazil.
Hllytchaikra Ferraz Fehlberg   +8 more
core   +1 more source

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