Results 101 to 110 of about 390,519 (313)

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

A Newcastle disease outbreak in backyard and free-range poultry in Slovenia

Frontiers in Veterinary Science
Newcastle disease (ND) is a highly contagious and economically important viral disease of poultry, caused by virulent strains of Orthoavulavirus javaense (OAVJ).
Zoran Žlabravec, Brigita Slavec, Alenka Dovč, Aleksandra Hari, Joško Račnik, Jedrt Maurer Wernig, Edoardo Giussani, Elisa Palumbo, Maria Varotto, Isabella Monne, Uroš Krapež   +10 more
doaj   +1 more source

New record of the Oriental house rat, Rattus tanezumi, in Nepal inferred from mitochondrial Cytochrome B gene sequences

Mitochondrial DNA. Part B. Resources, 2018
This study determines the presence of R. tanezumi from in Nepal using morphological and molecular analyses. Morphologically, it is indistinguishable with R. rattus owing to similar fur colour and morphometric data.
Pradeep Adhikari, Sang-Hyun Han, Yoo-Kyung Kim, Tae-Wook Kim, Tej Bahadur Thapa, Naresh Subedi, Amar Kunwar, Maniram Banjade, Hong-Shik Oh   +8 more
doaj   +1 more source

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

Molecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak, Iva Staniczková Zambo, Matěj Přikryl, Peter Múdry, Danica Zapletalová, Jarmila Navrátilová, Jiří Navrátil, Jan Šmarda, Liudmyla Drobot, Petr Beneš, Lucia Knopfová   +10 more
wiley   +1 more source

A case study of critical points for the entry and spread of Salmonella Infantis in a broiler farm

Irish Veterinary Journal
Salmonella Infantis is a zoonotic pathogen that frequently persists in broiler production systems, posing a risk to food safety and animal health. Understanding its entry and spread in these systems can inform control measures and reduce contamination. A
Bojan Papić, Jasna Mićunović, Brigita Slavec, Neva Šemrov, Olga Zorman Rojs, Jana Avberšek   +5 more
doaj   +1 more source

Detection of Leishmania spp. in Small Non-Flying Mammals (Didelphimorphia and Rodentia) from Bahia, Northeast Brazil

This study aimed to identify Leishmania species in small non-flying mammals captured in semi-deciduous forest fragments of the Atlantic Forest and pastures in the Southwest region of Bahia state, Northeast Brazil.
Hllytchaikra Ferraz Fehlberg, Anaiá da Paixão Sevá, Graziela Baroni de Souza, Bianca Mendes Maciel, Beatris Felipe Rosa, Fabiana Lessa Silva, Cássia Matos Ribeiro, George Rêgo Albuquerque, Martin Roberto Del Valle Alvarez   +8 more
core   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Himalayan Vultures in Khodpe, far-west Nepal: is there any threat?

Journal of Threatened Taxa, 2015
There is evidence that Himalayan Vulture Gyps himalayensis is susceptible to the veterinary drug diclofenac, which is responsible for the decline of other Gyps species across South Asia.
Manoj Kumar Joshi, Mukesh Kumar Chalise, Anand Chaudhary, Hem Bahadur Katuwal   +3 more
doaj   +1 more source

Isotope data of small mammals

, 2019
Carbon and nitrogen isotope data in small mammals from the flooded meadow; this is excell file with raw values from all studied ...
Marius Jasiulionis (7063595), Linas Balčiauskas (3277077), Balčiauskas, Linas, Balčiauskienė, Laima, Raminta Skipitytė (7063592), Laima Balčiauskienė (4241722), Skipitytė, Raminta, Jasiulionis, Marius   +7 more
core   +1 more source

Establishing an assay to evaluate d‐amino acid oxidase enzyme kinetics and inhibition using WST‐8 redox dye

FEBS Open Bio, EarlyView.
This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake, Yuki Enoki, Yuka Nakazawa, Kazuaki Taguchi, Kazuaki Matsumoto   +4 more
wiley   +1 more source