Results 101 to 110 of about 777,845 (296)

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

open access: yesFEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon   +6 more
wiley   +1 more source

Small mammal survey on agricultural land during conversion and into full organic production [PDF]

open access: yes, 2002
This report was presented at the UK Organic Research 2002 Conference. Loss of food and suitable habitat due to modern intensive farming and the decline of mixed farming systems has lead to a reduction in numbers of small mammals on farmland in the UK ...
Burke, Jean, Taylor, Nick
core  

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

open access: yesFEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li   +8 more
wiley   +1 more source

Prevalence and Genotype Allocation of Pathogenic Leptospira Species in Small Mammals from Various Habitat Types in Germany.

open access: yesPLoS Neglected Tropical Diseases, 2016
Small mammals serve as most important reservoirs for Leptospira spp., the causative agents of Leptospirosis, which is one of the most neglected and widespread zoonotic diseases worldwide. The knowledge about Leptospira spp.
Anna Obiegala   +6 more
doaj   +1 more source

Meta‐analysis fails to show any correlation between protein abundance and ubiquitination changes

open access: yesFEBS Open Bio, EarlyView.
We analyzed over 50 published proteomics datasets to explore the relationship between protein levels and ubiquitination changes across multiple experimental conditions and biological systems. Although ubiquitination is often associated with protein degradation, our analysis shows that changes in ubiquitination do not globally correlate with changes in ...
Nerea Osinalde   +3 more
wiley   +1 more source

Probiotic effect of B. subtilis PS-216 in broiler chickens: modulation of weight, feed conversion, short chain fatty acids, microbiota and meat quality

open access: yesAnimal Microbiome
Bacillus-based probiotics are recognized as safe and effective alternatives to antibiotic growth promoters in poultry production. This study evaluated the effects of Bacillus subtilis PS-216 on broiler performance, gut health, and meat quality.
Katarina Šimunović   +10 more
doaj   +1 more source

Establishing an assay to evaluate d‐amino acid oxidase enzyme kinetics and inhibition using WST‐8 redox dye

open access: yesFEBS Open Bio, EarlyView.
This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake   +4 more
wiley   +1 more source

Comparative immunohistochemical characterisation of a teratoma in a domestic duck (Anas platyrhynchos) and a teratocarcinoma in a muscovy duck (Cairina moschata)

open access: yesActa Veterinaria Scandinavica
Background Neoplasms consisting of two or more germinal layers are classified as teratomas if benign or as teratocarcinomas if malignant. Teratomas are rare tumours occurring in a wide range of species including mammals, birds and reptiles and only a few
Deborah Johanna Eikelberg   +5 more
doaj   +1 more source

Iron homeostasis disruption and lipid peroxidation in skeletal muscle during short‐term immobilization

open access: yesFEBS Open Bio, EarlyView.
14‐day casting‐induced immobilization reduced gastrocnemius muscle mass and increased non‐heme iron and ferritin heavy chain levels. Despite iron accumulation, transferrin receptor 1 and iron regulatory protein 2 were paradoxically upregulated. Lipid peroxidation was elevated without compensatory antioxidant responses.
Haruka Yokogawa   +2 more
wiley   +1 more source

Diversity and conservation status of small mammals in Kelantan, Malaysia [PDF]

open access: yesSongklanakarin Journal of Science and Technology (SJST), 2016
There is little information and research on the diversity of the small mammals in Kelantan. Thus, a series of wildlife surveys were done at five localities in Kelantan to further elucidate the diversity of small mammals in this state.
Jayaraj Vijaya Kumaran   +6 more
doaj  

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