Results 221 to 230 of about 787,224 (277)

Circular RNA PTPN4 Contributes to Blood‐Brain Barrier Disruption during Early Epileptogenesis

Advanced Science, EarlyView.
Epileptic condition induces CircPTPN4 upregulation, which promotes ECE‐1 expression through competitive sequestration of miR‐145a‐5p. The elevated ECE‐1 catalyzes the ET‐1 production, leading to p38/MAPK pathway activation and subsequent downregulation of tight junction protein expression. This cascade results in increased BBB permeability and enhanced
Jiurong Yang, Yang Hu, Feiyu Wang, Xintao Peng, Honggang Qi, Yuanyuan Yao, Canyu Zhang, Lijie Zhou, Xuemei Liang, Kang Xu, Cong Zhang, Aifeng Zhang, Chen Chen, Yu Zeng, Chenchen Zhang, Guangming Gan, Xinjian Zhu   +16 more
wiley   +1 more source

Molecular detection and typing of pathogenic <i>Leptospira</i> species from livestock and small mammals in Uganda. [PDF]

Epidemiol Infect
Alinaitwe L, Wainaina M, Dürr S, Kankya C, Kivali V, Bugeza J, Aturinda CJ, Lubega A, Mayer-Scholl A, Hoona JJ, Bahn P, Hammerl JA, Roesel K, Cook EAJ, Richter MH.   +14 more
europepmc   +1 more source

BioCNTs Mediated Delivery of Systemically Mobile Small RNAs via Leaf Spray to Control Both Tomato DNA and RNA Viruses

Advanced Science, EarlyView.
A carbon nanotube‐based biopesticide system (BioCNTs) enables efficient delivery and systemic movement of RNAi molecules to control major tomato viruses. By integrating shRNA and tRNA‐like structures (TLS) with BioCNTs, this green and scalable approach achieves long‐term silencing and high antiviral efficacy through simple foliar spraying.
Xuedong Liu, Xiaofei Liang, Zipeng Cai, Zheng Liu, Xuefeng Wang, Changyong Zhou, Mengji Cao, Sijia Liu   +7 more
wiley   +1 more source

Faunal and Ecological Analysis of Gamasid Mites (Acari: Mesostigmata) Associated with Small Mammals in Yunnan Province, Southwest China. [PDF]

Insects
Yin PW, Peng PY, Guo XG, Song WY, Ren TG, Zhao YF, Dong WG, Jin DC.   +7 more
europepmc   +1 more source

Structural and Functional Characterization of EXPO‐Derived Extracellular Vesicles in Plants

Advanced Science, EarlyView.
In this study, 3D electron tomography (ET), cryo‐ET, and immunogold transmission electron microscopy (TEM) are employed to characterize plant extracellular vesicles (EVs) under physiological conditions. EVs are classified into three distinct categories according to their size, content, and molecular‐marker profiles. Furthermore, Exo70E2‐positive medium
Jiayang Gao, Yanbin Li, Shengqi Zhang, Yilin He, Zhiqi Liu, Juan Wang, Jingmin Hua, Jinyu Chen, Junru Zhong, Huan Zhong, Yiji Xia, Yong Cui, Liwen Jiang   +12 more
wiley   +1 more source

Comparative study on <i>Bartonella</i> infection in spleen and kidney of small mammals from Mile City and Lianghe County, Yunnan Province. [PDF]

Front Vet Sci
Fu R, Yin JX, He P, Chen Y, Luo Y, Liu PG, Guo SL.   +6 more
europepmc   +1 more source

Nanoscale Mapping of the Subcellular Glycosylation Landscape

Advanced Science, EarlyView.
Using multiplexed super‐resolution imaging with fluorophore‐labeled lectins, this study reports intracellular glycosylation at the nanoscale across organelles and synaptic specializations. Extending glycan analysis beyond the cell surface, Glyco‐STORM reveals distinct glycosylation nanodomains in the ER, Golgi, lysosomes, and synaptic sites.
Helene Gregoria Schroeter, Steffen Sass, Mike Heilemann, Thomas Kuner, Maja Klevanski   +4 more
wiley   +1 more source

One Health Surveillance for SARS-CoV-2 in Non-Human Primates and Small Mammals in Minas Gerais, Brazil. [PDF]

Pathogens
Almeida-Souza PA, Silva TGM, Penha GB, de Jesus Teixeira T, Oliveira-Silva R, Celestino IA, Gonçalves-Dos-Santos ME, de Oliveira CH, Dos Santos Nunes Ferreira A, Gusmão EM, Ottone VO, Simonini-Teixeira D, Campos FS, Roehe PM, de Oliveira LC, Teixeira MM, Abreu FVS, Oliveira DB.   +17 more
europepmc   +1 more source

Perfluorooctanoic Acid Exposure Causes Macrophage Ammonia Retention and Induces Spontaneous Miscarriages

Advanced Science, EarlyView.
PFOA exposure induces pregnancy loss by promoting glutaminolysis, which further causes ammonia accumulation in macrophages. Cellular ammonia retention results in damage to mitochondria and lysosomes, which leads to cell death eventually. Impaired lysosomes also decrease the secretion of the Cathepsin B (CTSB), and attenuate macrophage infiltration and ...
Yongbo Zhao, Yijun Zhang, Hanyu Rao, Jiani Sun, Zhiyi Pan, Liping Jin, Yan Zhao   +6 more
wiley   +1 more source

Preliminary study of canine distemper virus transmission from small mammals to Malayan tiger at Kampung Besul Lama, Terengganu, Malaysia. [PDF]

Vet World
Lazarus BA, Sadali MFM, Kamal FM, Hua KK, Wahab RA, Kaderi MA, Abdullah ML, Azizan TRPT, Ahmad H.   +8 more
europepmc   +1 more source