Results 181 to 190 of about 645,880 (357)

Discovery of a Covalent Kinase Inhibitor from a DNA-Encoded Small-Molecule Library × Protein Library Selection

, 2017
Alix I Chan, Lynn M. McGregor, Tara Jain, David R. Liu   +3 more
openalex   +2 more sources

Geometric Optimization and Mechanical Performance Enhancement of Auxetic Structures for High‐Impact Applications Through Fused Deposition Modeling

Advanced Engineering Materials, EarlyView.
This study explores the mechanical performance of three auxetic structures, identifying a re‐entrant‐star hybrid as the most effective for impact absorption. Finite element simulations and experiments demonstrate significant gains in energy absorption and flexural strength after geometric optimization. This study investigates the mechanical performance
Malik Hassan, Manjusri Misra, Alexander Bardelcik, Stefano Gregori, Amar K. Mohanty   +4 more
wiley   +1 more source

Is Young's Modulus a Critical Coating Property Determining Fouling‐Release Performance of Marine Coatings?

Advanced Engineering Materials, EarlyView.
The release of foulers from protective marine coatings is determined by several interrelated material properties, including the strength of Young's modulus, the flexibility of chain segments, the surface free energy, and the magnitude of hydrodynamic stress.
Johann C. Schaal, Andreas Brinkmann, Andreas Hartwig   +2 more
wiley   +1 more source

High throughput screening of a small molecule chemical library reveals novel therapeutic potential drugs in treatment of diabetic retinopathy

, 2021
Gabriella Acosta, Finny Monickaraj, Arup Das   +2 more
openalex   +1 more source

Trace Nickel Activated Biphasic Core‐CuOii/Shell‐CuOi Secondary Microspheres Enable Room Temperature Parts‐Per‐Trillion‐Level NO2 Detection

Advanced Engineering Materials, EarlyView.
An idea of designing novel sensors is proposed by creating appropriate Schottky barriers and vacancies between isomorphous Core‐CuOii/ Shell‐CuOi secondary microspheres and enhancing catalytic and spill‐over effects, and electronegativity via spontaneous biphasic separation, self‐assembly, and trace‐Ni‐doping.
Bala Ismail Adamu, Peipei Chen, Shafia Mukhtar Ibrahim, Mukhtar Lawan Adam, Attia Falak, Mokhotjwa Simon Dhlamini, Hanfu Wang, Lingxiang Jiang, Weiguo Chu   +8 more
wiley   +1 more source

Advancing Research on Biomaterials and Biological Materials with Scanning Electron Microscopy under Environmental and Low Vacuum Conditions

Advanced Engineering Materials, EarlyView.
Herein, environmental scanning electron microscopy (ESEM) is discussed as a powerful extension of conventional SEM for life sciences. By combining high‐resolution imaging with variable pressure and humidity, ESEM allows the analysis of untreated biological materials, supports in situ monitoring of hydration‐driven changes, and advances the functional ...
Jendrian Riedel, Lea Dierker, Antoine Eyram Kwame, Kim Nora Wagner, Jonas J. Unterholzner, Jan‐Henning Dirks, Dorothea Brüggemann   +6 more
wiley   +1 more source

Small Molecule Modulator of the mTORC2 Pathway Discovered from a DEL Library Designed to Bind to Pleckstrin Homology Domains [PDF]

Arthur Gonse, Jelena Gajić, Jean‐Pierre Daguer, Sofía Barluenga, Robbie Loewith, Nicolas Winssinger   +5 more
openalex   +1 more source

Supplementary Material from Evaluation of a chemical library of small-molecule Dishevelled antagonists that suppress tumor growth by down-regulating T-cell factor–mediated transcription

, 2023
Liang You, Zhidong Xu, Chandanamali Punchihewa, David M. Jablons, Naoaki Fujii   +4 more
openalex   +1 more source

Bimetallic (NiFe) and Trimetallic (NiFeCr) Nanoalloys from Metal Oxides Using a Microwave Hydrogen Plasma

Advanced Engineering Materials, EarlyView.
Bimetallic (NiFe) and trimetallic (NiFeCr) nanoalloys (NAs) are synthesized using corresponding oxide mixtures using microwave hydrogen plasma within a few milliseconds. The process simultaneously 1) reduces metal oxides to metals; 2) downsizes the particles from micrometers to nanometers; and 3) blends the metals to form NAs.
Sachin Kumar, Mohammad Kazemi, Zichang Xiong, Thomas Cameron, Julian Held, Uwe Kortshagen   +5 more
wiley   +1 more source

Comprehensive Search for GPCR Compounds which Can Enhance MafA and/or PDX-1 Expression Levels Using a Small Molecule Compound Library [PDF]

, 2023
Hideaki Kaneto, Atsushi Obata, Masashi Shimoda, Tomohiko Kimura, Yoshiyuki Obata, Tomoko Ikeda, Saeko Moriuchi, Shuhei Nakanishi, Tomoatsu Mune, Kohei Kaku   +9 more
openalex   +1 more source