Results 211 to 220 of about 645,880 (357)

Ice Lithography: Recent Progress Opens a New Frontier of Opportunities

Advanced Functional Materials, EarlyView.
This review focuses on recent advancements in ice lithography, including breakthroughs in compatible precursors and substrates, processes and applications, hardware, and digital methods. Moreover, it offers a roadmap to uncover innovation opportunities for ice lithography in fields such as biological, nanoengineering and microsystems, biophysics and ...
Bingdong Chang, Gwendoline A. E. Anand, Rubaiyet Haque, Dylan A. Chiaro, Mona Sharma, Andrew R. Williams, Frank Niklaus, Daryl W. Yee, Gavin M. King, Anpan Han   +9 more
wiley   +1 more source

Chemical synthesis of small molecule libraries around the p-benzoquinone scaffold

, 2008
Valentina Wachter
openalex   +1 more source

Inhibitors of Leishmania GDP-Mannose Pyrophosphorylase Identified by High-Throughput Screening of Small-Molecule Chemical Library [PDF]

, 2010
Kurt Lackovic, John P. Parisot, Nerida Sleebs, Jonathan B. Baell, Laurent Debien, Keith G. Watson, Joan Curtis, Emanuela Handman, Ian P. Street, Łukasz Kedzierski   +9 more
openalex   +1 more source

Expanding Chemical Space of Nucleic Acid Nanoparticles for Tunable Antiviral‐Like Immunomodulatory Responses and Potent Adjuvant Activity

Advanced Functional Materials, EarlyView.
We introduce a nucleic acid nanoparticle (NANP) platform designed to be rrecognized by the human innate immune system in a regulated manner. By changing chemical composition while maintaining constant architectural parameters, we identify key determinants of immunorecognition enabling the rational design of NANPs with tunable immune activation profiles
Martin Panigaj, Hannah S. Newton, Jian Wang, Laxmi Pandey, Yelixza I. Avilla, Phong Nguyen, Morgan Chandler, Justin Halman, Yasmine Radwan, Stephanie Smith, Elijah Edmondson, Simone Difilippantonio, Chelsea Sanders, Bao Tran, Yongmei Zhao, Shaojun Xie, Edward Cedrone, Barry W. Neun, Meni Wanunu, Nikolay V. Dokholyan, Marina A. Dobrovolskaia, Kirill A. Afonin   +21 more
wiley   +1 more source

Allosteric “beta-blocker” isolated from a DNA-encoded small molecule library [PDF]

, 2017
Seungkirl Ahn, Alem W. Kahsai, Biswaranjan Pani, Qinting Wang, Shuai Zhao, Alissa L. Wall, Ryan T. Strachan, Dean P. Staus, Laura M. Wingler, Lillian Sun, Justine Sinnaeve, Minjung Choi, Ted Cho, Thomas T. Xu, Gwenn M. Hansen, Michael B. Burnett, Jane E. Lamerdin, Daniel L. Bassoni, Bryant J. Gavino, Gitte Husemoen, Eva K. Olsen, Thomas Franch, Stefano Costanzi, Xin Chen, Robert J. Lefkowitz   +24 more
openalex   +1 more source

Peptide Sequencing With Single Acid Resolution Using a Sub‐Nanometer Diameter Pore

Advanced Functional Materials, EarlyView.
To sequence a single molecule of Aβ1−42–sodium dodecyl sulfate (SDS), the aggregate is forced through a sub‐nanopore 0.4 nm in diameter spanning a 4.0 nm thick membrane. The figure is a visual molecular dynamics (VMD) snapshot depicting the translocation of Aβ1−42–SDS through the pore; only the peptide, the SDS, the Na+ (yellow/green) and Cl− (cyan ...
Apurba Paul, Archith Rayabharam, Lisa Almonte, Eveline Rigo, Joshy Joseph, Ashutosh Kumar, Zhuxin Dong, Narayana Aluru, Gregory Timp   +8 more
wiley   +1 more source

On-DNA Platform Molecules Based on a Diazide Scaffold II: A Compact Diazide Platform Designed for Small-Molecule Drug Discovery. [PDF]

Int J Mol Sci
Miyachi H, Koshimizu M, Suzuki M.
europepmc   +1 more source

Ultrahigh‐Yield, Multifunctional, and High‐Performance Organic Memory for Seamless In‐Sensor Computing Operation

Advanced Functional Materials, EarlyView.
Molecular engineering of a nonconjugated radical polymer enables a significant enhancement of the glass transition temperature. The amorphous nature and tunability of the polymer, arising from its nonconjugated backbone, facilitates the fabrication of organic memristive devices with an exceptionally high yield (>95%), as well as substantial ...
Daeun Kim, Jaehyoung Ko, Namju Kim, Quynh H. Nguyen, Hoyeon Lee, Joohwan Eo, Seongeon Jin, Ji Eon Kwon, Seung‐Yeol Jeon, Youngdo Jeong, Dongseok Kwon, Sung Gap Im, Sanghan Lee, Byung Chul Jang, Yongho Joo   +14 more
wiley   +1 more source

Unusually broad-spectrum small-molecule sensing using a single protein scaffold. [PDF]

Proc Natl Acad Sci U S A
Tian H, Beltrán J, George W, Lenert-Mondou C, Seder N, Davis ZI, Swift SD, Girke T, Whitehead TA, Wheeldon I, Cutler SR.   +10 more
europepmc   +1 more source

Panel docking of small-molecule libraries — Prospects to improve efficiency of lead compound discovery

, 2015
Pakornwit Sarnpitak, Prashant Mujumdar, Paul Taylor, Megan Cross, Mark J. Coster, Alain‐Dominique Gorse, Mikhail Krasavin, Andreas Hofmann   +7 more
openalex   +2 more sources