Results 241 to 250 of about 194,605 (341)

Bioxolography Using Diphenyliodonium Chloride and N‐Vinylpyrrolidone Enables Rapid High‐Resolution Volumetric 3D Printing of Spatially Encoded Living Matter

Advanced Materials, EarlyView.
Bioxolography, a novel volumetric 3D‐bioprinting technique, enables rapid and high‐resolution fabrication of >1 cm3 engineered living materials. A newly developed three‐component photoinitiator system significantly enhances the photoreactivity of gelatin methacryloyl‐based bioresins, allowing for precise xolographic bioprinting.
Alexis Wolfel, Castro Johnbosco, Annalise Anspach, Marieke Meteling, Jos Olijve, Niklas Felix König, Jeroen Leijten   +6 more
wiley   +1 more source

Radical TADF: Quartet‐Derived Luminescence with Dark TEMPO

Advanced Materials, EarlyView.
A new class of luminescent organic quantum materials is introduced, formed by attaching a stable radical to TADF chromophores. Due to ferromagnetic exchange coupling, a high‐spin quartet state forms upon excitation, which can thermally access a bright state.
Sebastian Gorgon, Petri Murto, Daniel G. Congrave, Lujo Matasovic, Andrew D. Bond, Victor Riesgo‐Gonzalez, William K. Myers, Hugo Bronstein, Richard H. Friend   +8 more
wiley   +1 more source

New strategies to enhance the efficiency and precision of drug discovery. [PDF]

Front Pharmacol
An Q, Huang L, Wang C, Wang D, Tu Y.
europepmc   +1 more source

Polyanhydride‐Based Microparticles for Programmable Pulsatile Release of Diphtheria Toxoid (DT) for Single‐Injection Self‐Boosting Vaccines

Advanced Materials, EarlyView.
This study presents a polyanhydride‐based delivery platform for single‐injection, self‐boosting vaccines. The system enables programmable, pulsatile release of diphtheria toxoid with high antigen recovery and is guided by machine learning for tunability. In vivo results show immune responses comparable to multi‐dose regimens, highlighting its potential
Linzixuan Zhang, Ruiqing Xiao, Wenhao Gao, Johnny Garcia, Xinyan Pan, John L. Daristotle, Timothy Forster, Jooli Han, Mehr Chaddah, Dhruv Varshney, Nandita Menon, Kevin J. McHugh, Benjamin J. Pedretti, Jing Ying Yeo, Xin Yang, Sydney MacDonald, Robert Langer, Ana Jaklenec   +17 more
wiley   +1 more source

Photoaffinity enabled transcriptome-wide identification of splice modulating small molecule-RNA binding events in native cells. [PDF]

RSC Chem Biol
Shah R, Yan W, Rigal J, Mullin S, Fan L, McGregor L, Krueger A, Renaud N, Byrnes A, Thomas JR.   +9 more
europepmc   +1 more source

A Novel Algorithm for the Virtual Screening of Extensive Small Molecule Libraries Against ERCC1/XPF Protein-Protein Interaction for the Identification of Therapeutic Resistance-Bypassing Small Anticancer Molecules

Tuğba Gül Inci, Serap Acar, Dilek Turgut‐Balik   +2 more
openalex   +1 more source

In Vitro Selection of a DNA-Templated Small-Molecule Library Reveals a Class of Macrocyclic Kinase Inhibitors

, 2010
Ralph E. Kleiner, Christoph E. Dumelin, Gerald C. Tiu, Kaori Sakurai, David R. Liu   +4 more
openalex   +1 more source

Mussel‐Inspired Molecular Strategies for Fabricating Functional Materials With Underwater Adhesion and Self‐Healing Properties

Advanced Materials, EarlyView.
This review systematically examines the nanomechanical mechanisms of mussel‐inspired molecular interactions, primarily investigated by direct force measurement techniques such as surface forces apparatus and atomic force microscopy. The macroscopic adhesive and self‐healing performances of mussel‐inspired functional materials, including coacervates ...
Pan Huang, Hongjian Zhang, Hongbo Zeng
wiley   +1 more source

Induced cell phenotype activity recording of DNA-tagged ligands. [PDF]

RSC Chem Biol
Sander PN, Gillen Miller JT, Lairson LL.
europepmc   +1 more source

Large library docking and biophysical analysis of small molecule TMPRSS2 inhibitors

Bryan J. Fraser, Nicholas Young, Brian J. Bender, Stefan Gahbauer, Olzhas Ilyassov, R Wilson, Yanjun Li, Almagul Seitova, André Luiz Lourenço, Dawoon Chung, Conner Bardine, François Bénard, Brian K. Shoichet, Charles S. Craik, C.H. Arrowsmith   +14 more
openalex   +1 more source