Results 101 to 110 of about 442,180 (329)
Advanced Science, EarlyView.Box C/D snoRNP complex regulates protein translation. This study identifies ZNHIT3 as a key component of the complex and ensures normal protein expression, including transcription factors orchestrating cell fate commitment, during early mouse embryogenesis.
Guanghui Yang, Qiliang Xin, Jurrien Dean
wiley +1 more source
Maturation of small nucleolar RNAs: from production to function
RNA Biology, 2023 Small Nucleolar RNAs (snoRNAs) are an abundant group of non-coding RNAs with well-defined roles in ribosomal RNA processing, folding and chemical modification. Besides their classic roles in ribosome biogenesis, snoRNAs are also implicated in several other cellular activities including regulation of splicing, transcription, RNA editing, cellular ...
Sarah F. Webster, Homa Ghalei
openaire +3 more sources
Localisation of the Ki-67 antigen within the nucleolus: Evidence for a fibrillarin-deficient region of the dense fibrillar component [PDF]
, 1996 The Ki-67 antigen is detected in proliferating cells in all phases of the cell division cycle. Throughout most of interphase, the Ki-67 antigen is localised within the nucleolus.
Kill, IR
core
A monopartite nuclear localization sequence regulates nuclear targeting of the actin binding protein myopodin [PDF]
, 2005 Myopodin is an actin bundling protein that shuttles between nucleus and cytoplasm in response to cell stress or during differentiation. Here, we show that the myopodin sequence (58)KKRRRRARK(66), when tagged to either enhanced green fluorescent protein ...
De Corte, Veerle +6 more
core +1 more source
Long Noncoding RNAs in Metabolic Syndrome Related Disorders
Mediators of Inflammation, 2016 Ribonucleic acids (RNAs) are very complex and their all functions have yet to be fully clarified. Noncoding genes (noncoding RNA, sequences, and pseudogenes) comprise 67% of all genes and they are represented by housekeeping noncoding RNAs (transfer RNA (
Magdalena Losko +2 more
doaj +1 more source
snR30/U17 Small Nucleolar Ribonucleoprotein: A Critical Player during Ribosome Biogenesis
Cells, 2020 The small nucleolar RNA snR30 (U17 in humans) plays a unique role during ribosome synthesis. Unlike most members of the H/ACA class of guide RNAs, the small nucleolar ribonucleoprotein (snoRNP) complex assembled on snR30 does not direct pseudouridylation
Timothy John Vos, Ute Kothe
doaj +1 more source
Viruses, 2022 The nucleolus is a subnuclear compartment whose primary function is the biogenesis of ribosomal subunits. Certain viral infections affect the morphology and composition of the nucleolar compartment and influence ribosomal RNA (rRNA) transcription and ...
Nofar Atari +9 more
doaj +1 more source
Molecular Medicine Reports, 2018 Long non-coding RNAs (lncRNAs) offer great potential as cancer biomarkers. Owing to the limited sensitivity and specificity of α-fetoprotein (AFP) for the diagnosis of hepatocellular carcinoma (HCC), the present study used an lncRNA microarray to screen ...
Shoubao Gao +4 more
semanticscholar +1 more source
Advanced Science, EarlyView.Abstract Liver cancer stem cells (CSCs) account for tumor initiation, heterogeneity and therapy resistance. However, the role of small nucleolar RNAs (snoRNAs) in the regulation of liver CSCs remains largely unclear. Here, this work identifies a conserved H/ACA box snoRNA SNORA74A which is highly expressed in liver CSCs.
Ziheng Zhou +12 more
wiley +1 more source
Unusual features of pomoviral RNA movement [PDF]
, 2013 This work is partially supported by the Scottish Government’s Rural and Environment Science and Analytical Services (RESAS) DivisionPotato mop-top pomovirus (PMTV) is one of a few viruses that can move systemically in plants in the absence of the capsid ...
Bragard, Claude +6 more
core +1 more source