Results 101 to 110 of about 202,981 (234)

The Benyvirus RNA Silencing Suppressor Is Essential for Long-Distance Movement, Requires Both Zinc-Finger and NoLS Basic Residues but Not a Nucleolar Localization for Its Silencing-Suppression Activity

open access: yesMolecular Plant-Microbe Interactions, 2013
The RNA silencing-suppression properties of Beet necrotic yellow vein virus (BNYVV) and Beet soil-borne mosaic virus (BSBMV) cysteine-rich p14 proteins have been investigated.
Sotaro Chiba   +7 more
doaj   +1 more source

Small nucleolar RNA 78 promotes the tumorigenesis in non-small cell lung cancer

open access: yesJournal of experimental & clinical cancer research : CR, 2015
BackgroundAccumulating evidence suggests that dysregulated snoRNA may play a role in the development of malignancy. In the present study, we investigated the role of SNORD78 in the tumorigenesis of non-small cell lung cancer (NSCLC).MethodsWe determined ...
D. Zheng   +10 more
semanticscholar   +1 more source

Analysis of Non‐Coding RNAs and N6‐Methyladenosine‐Modified Genes in Response to flg22 in Grape Immunity

open access: yesPlant Biotechnology Journal, EarlyView.
ABSTRACT Grape (Vitis vinifera) is susceptible to fungal pathogens and, consequently, severe yield losses. Investigating the immune mechanisms of the disease‐resistant Chinese wild grapes is crucial for developing sustainable disease resistance technologies.
Ruiwei Duan   +5 more
wiley   +1 more source

DNA Hypomethylation Is One of the Epigenetic Mechanisms Involved in Salt‐Stress Priming in Soybean Seedlings

open access: yesPlant, Cell &Environment, EarlyView.
ABSTRACT Salt‐stress priming enhances the tolerance of plants against subsequent exposure to a similar stress. Priming‐induced transcriptomic reprogramming is mediated by multiple epigenetic mechanisms, the best known of which is histone modifications. However, not much is known about other epigenetic responses.
Wai‐Shing Yung   +7 more
wiley   +1 more source

Unveiling roles of non‐coding RNAs in cancer through advanced technologies

open access: yesQuantitative Biology, Volume 13, Issue 4, December 2025.
Abstract Non‐coding RNAs (ncRNAs) have emerged as key regulators in tumorigenesis. In this perspective, we briefly review the significance of ncRNA in cancer biology and highlight recent technological advancements in characterization of ncRNA in cancer research. Specifically, we discuss how these advanced approaches, such as Patho‐DBiT, CRISPR screens,
Runhao Wang, Leng Han
wiley   +1 more source

Notch NICD domains form biomolecular condensates

open access: yesJournal of Cell Communication and Signaling, Volume 19, Issue 3, September 2025.
Abstract Biomolecular condensates are a quickly emerging area of research that strongly impacts how we view the inner workings of the cell itself. Here, we explore the connection between the Notch signaling pathway and nuclear condensate localization.
Tana R. Gazdik   +8 more
wiley   +1 more source

The mRNA Translation Inhibitor Vioprolide A Prevents Inflammatory Pain‐Like Behaviour With Limited Action on Already Established Pain‐Like Behaviour in Mice

open access: yesEuropean Journal of Pain, Volume 29, Issue 8, September 2025.
ABSTRACT Background Accumulating evidence indicates that pharmacological inhibition of the translational machinery is a therapeutic strategy for various diseases. However, whether inhibitors of mRNA translation might be suitable for pain therapy remains poorly understood. Here, we tested the potential analgesic effects of the natural product vioprolide
Patrick Engel   +6 more
wiley   +1 more source

Cellular Senescence in Cancer: Mechanisms, Roles in Tumor Progression, and Therapeutic Implications

open access: yesMedComm – Oncology, Volume 4, Issue 3, September 2025.
Senescent tumor cells in TME exhibit dual roles. “Angels” secrete SASPs/DAMPs to boost immunological clearance and antitumor immunity via MHC‐I upregulation; “Demons” produce tumor‐promoting SASPs recruiting MDSCs to drive malignancy. ABSTRACT Cellular senescence, a state of irreversible cell cycle arrest accompanied by a senescence‐associated ...
Jingrui Yan   +5 more
wiley   +1 more source

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