All Small Nuclear RNAs (snRNAs) of the [U4/U6.U5] Tri-snRNP Localize to Nucleoli; Identification of the Nucleolar Localization Element of U6 snRNA [PDF]
Susan A. Gerbi, Thilo S. Lange
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Genetic risk and polygenic risk score assessment of prediabetes and progression to type 2 diabetes
Abstract Aims To identify susceptibility loci to prediabetes and evaluate the performance of existing polygenic risk scores (PGS) for type 2 diabetes (T2D) in predicting prevalent prediabetes and progression to diabetes. Materials and Methods We conducted a case–control Genome‐Wide Association Study (GWAS) on Qatar Biobank (QBB) participants with ...
Usama Aliyu+5 more
wiley +1 more source
Clinical significance and prognostic value of small nucleolar RNA SNORA38 in breast cancer. [PDF]
Song J+7 more
europepmc +1 more source
A Physical Interaction between Gar1p and Rnt1p Is Required for the Nuclear Import of H/ACA Small Nucleolar RNA-Associated Proteins [PDF]
Annie Tremblay+6 more
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TaSED interacts with TaSPA synergistically regulating SDS‐sedimentation volume in bread wheat
Wheat TaSED is a positive regulator of SDS‐sedimentation volume, an indicator of gluten strength and thus baking properties. TaSED interacts with the transcription factor TaSPA regulating wheat storage protein gene expression, altering protein composition and affecting SDS‐sedimentation volume, providing a valuable genetic resource for improving wheat ...
Shanshan Zhai+13 more
wiley +1 more source
Graph Convolutional Network and Contrastive Learning Small Nucleolar RNA (snoRNA) Disease Associations (GCLSDA): Predicting snoRNA-Disease Associations via Graph Convolutional Network and Contrastive Learning. [PDF]
Zhang L, Chen M, Hu X, Deng L.
europepmc +1 more source
Distinct Biogenesis Pathways for Human Telomerase RNA and H/ACA Small Nucleolar RNAs [PDF]
Dragony Fu, Kathleen Collins
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The TP53 tumor suppressor gene: From molecular biology to clinical investigations
Abstract Extensively studied over the past four decades, the TP53 gene has emerged as a pivotal watchman in cellular defense and a key factor in cancer biology. TP53 is the most frequently mutated gene in human malignancies, 50% of which carry alterations to it.
Panagiotis Baliakas, Thierry Soussi
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Non‐coding RNAs in plant stress responses: molecular insights and agricultural applications
Summary Non‐coding RNAs (ncRNAs) have emerged as crucial regulators in plant responses to environmental stress, orchestrating complex networks that finetune gene expression under both abiotic and biotic challenges. To elucidate this intricate ncRNA crosstalk, this review comprehensively summarizes recent advances in understanding the mechanisms of key ...
Xiaotong Chen+3 more
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