Results 91 to 100 of about 536,647 (305)

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Identification of microRNAs in normal and mantled oil palm fruit via 454 transcriptome sequencing (P053) [PDF]

, 2011
Small RNAs such as miRNAs and siRNAs play a critical role in post-transcriptional gene regulation and have been shown to control many genes involved in various biological processes including fruit development. Oil palm (Elaeis guineensis Jacq) belongs to
Jantasuriyarat, Chatchawan, Morcillo, Fabienne, Piriyapongsa, Jittima, Saensuk, Chatree, Tangphatsornruang, Sithichoke, Tragoonrung, Somvong, Tranbarger, Timothy John, Vanavichit, Apichart   +7 more
core  

Transcription of satellite DNAs in insects [PDF]

, 2011
Chromatin condensation is an important regulatory mechanism of gene silencing as well as gene activation for the hundreds of functional protein genes harbored in heterochromatic regions of different insect species.
D. Ugarkovic, FELICIELLO, ISIDORO, J. Brajkovic, Z. Pezer   +3 more
core   +1 more source

Sorting Out Small RNAs [PDF]

Cell, 2008
Small RNAs carry out their functions by guiding Argonaute (AGO) proteins to their targets. Diverse types of small RNAs and multiple AGO proteins exist in most eukaryotic species, but how small RNAs are sorted into specific AGO complexes remains unclear. Two papers in this issue (Mi et al., 2008; Montgomery et al., 2008) now reveal the importance of the
openaire   +2 more sources

tRNA-Derived Small RNA: A Novel Regulatory Small Non-Coding RNA [PDF]

Genes, 2018
Deep analysis of next-generation sequencing data unveils numerous small non-coding RNAs with distinct functions. Recently, fragments derived from tRNA, named as tRNA-derived small RNA (tsRNA), have attracted broad attention. There are mainly two types of tsRNAs, including tRNA-derived stress-induced RNA (tiRNA) and tRNA-derived fragment (tRF), which ...
Siqi Li, Zhengping Xu, Jinghao Sheng
openaire   +2 more sources

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

An endogenous small interfering RNA pathway in Drosophila [PDF]

, 2008
Drosophila endogenous small RNAs are categorized according to their mechanisms of biogenesis and the Argonaute protein to which they bind. MicroRNAs are a class of ubiquitously expressed RNAs of 22 nucleotides in length, which arise from structured ...
A Eulalio, A Stark, AA Aravin, Alexander Stark, AM Denli, Benjamin Czech, C Klattenhoff, Catherine Schlingeheyde, Colin D. Malone, D Galiana-Arnoux, E Allen, E Bernstein, E Yigit, F Jiang, Gregory J. Hannon, J Brennecke, J Jurka, J Pak, J Rehwinkel, James A. Wohlschlegel, JG Ruby, JG Ruby, Julius Brennecke, K Forstemann, K Forstemann, K Okamura, K Saito, K Saito, LS Gunawardane, Manolis Kellis, Monica Dus, N Bushati, Norbert Perrimon, Q Liu, Ravi Sachidanandam, Rui Zhou, T Sijen, VV Vagin, XH Wang, Y Lee, Y Tomari, YS Lee   +41 more
core   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source

Identification of small RNAs abundant in Burkholderia cenocepacia biofilms reveal putative regulators with a potential role in carbon and iron metabolism [PDF]

, 2017
Small RNAs play a regulatory role in many central metabolic processes of bacteria, as well as in developmental processes such as biofilm formation. Small RNAs of Burkholderia cenocepacia, an opportunistic pathogenic beta-proteobacterium, are to date not ...
Coenye, Tom, Kiekens, Sanne, Sass, Andrea   +2 more
core   +3 more sources

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source