Results 71 to 80 of about 5,862,706 (262)
Diverse and tissue-enriched small RNAs in the plant pathogenic fungus,
BMC Genomics, 2011 Background Emerging knowledge of the impact of small RNAs as important cellular regulators has prompted an explosion of small transcriptome sequencing projects.
Brown Douglas E +8 more
doaj +1 more source
Comprehensive Small RNA-Seq of Adeno-Associated Virus (AAV)-Infected Human Cells Detects Patterns of Novel, Non-Coding AAV RNAs in the Absence of Cellular miRNA Regulation. [PDF]
PLoS ONE, 2016 Most DNA viruses express small regulatory RNAs, which interfere with viral or cellular gene expression. For adeno-associated virus (AAV), a small ssDNA virus with a complex biphasic life cycle miRNAs or other small regulatory RNAs have not yet been ...
Catrin Stutika +6 more
doaj +1 more source
Data analysis to identify known small RNAs.
, 2016 (A) The numbers of sequenced small RNAs, which were further classified into known and unknown small RNAs in each sample. (B) The composition of identified known small RNAs such as tRNA, rRNA, snRNA, snoRNA, conserved miRNA, novel miRNA, and vsiRNA in ...
Sen Lian (413463) +4 more
core +1 more source
Small RNAs in epigenetic inheritance: from mechanisms to trait transmission
, 2021 International audienceInherited information is transmitted to progeny primarily by the genome through the gametes. However, in recent years, epigenetic inheritance has been demonstrated in several organisms, including animals.
Germano Cecere, Cecere, Germano
core +1 more source
FEBS Letters, EarlyView.Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil +3 more
wiley +1 more source
A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma
FEBS Letters, EarlyView.Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos +9 more
wiley +1 more source
Phase distribution of small RNAs.
, 2015 (A) Phase distribution and abundance of 21-nt small RNAs mapped onto the miR173ts_CHS transcripts. Paired sense and antisense 21-nt RNAs with 2-nt 3′ overhangs are consolidated to one small RNA unit. Processing cycles augment at 21-nt intervals.
Yao Han (572669) +4 more
core +1 more source
Inhibition of dipeptidyl peptidase 7 impairs lysophagy in LLOMe‐treated HepG2 cells
FEBS Letters, EarlyView.DPP7 inhibition delays ubiquitin‐dependent lysophagy by attenuating ubiquitin accumulation and the recruitment of SQSTM1 and LC3 to damaged lysosomes, resulting in delayed clearance of damaged lysosomes and impaired restoration of lysosomal homeostasis. Created using FigureLabs (Certificate ID: FL‐PUB‐20260922‐Z99XNX).
Na Yeon Park +8 more
wiley +1 more source
Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy
FEBS Letters, EarlyView.The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley +1 more source
Diversity in parasitic nematode genomes: the microRNAs of Brugia pahangi and Haemonchus contortus are largely novel [PDF]
, 2012 <b>BACKGROUND:</b> MicroRNAs (miRNAs) play key roles in regulating post-transcriptional gene expression and are essential for development in the free-living nematode Caenorhabditis elegans and in higher organisms.
Winter, A.D. +20 more
core +1 more source