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The Genetics of Small-Vessel Disease
Current Medicinal Chemistry, 2012Cerebral small-vessel disease (SVD) is a well-known cause of stroke, dementia and death, but its pathogenesis is not yet completely understood. The spectrum of neuroradiological manifestations associated with SVD is wide and may result from chronic and diffuse or acute and focal ischemia (leukoaraiosis and lacunar infarction) as well as from small ...
A. Bersano +6 more
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Migraine and small vessel diseases
Neurological Sciences, 2012It is remarkable that migraine is a prominent part of the phenotype of several genetic vasculopathies affecting small cerebral vessels, including cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy, retinal vasculopathy with cerebral leukodystrophy and hereditary infantile hemiparesis, retinal arteriolar ...
E, Agostoni, A, Rigamonti
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2020
‘Small vessel disease’ describes a combination of neuroradiological and clinical features that are due to an intrinsic disorder of the small cerebral arterioles, capillaries, and venules in varying proportions. It is very common, usually sporadic, although rare monogenic forms are well described. The commonest presentations are with stroke or cognitive
Fergus N Doubal +3 more
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‘Small vessel disease’ describes a combination of neuroradiological and clinical features that are due to an intrinsic disorder of the small cerebral arterioles, capillaries, and venules in varying proportions. It is very common, usually sporadic, although rare monogenic forms are well described. The commonest presentations are with stroke or cognitive
Fergus N Doubal +3 more
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2016
Lacunar strokes are strongly associated with hypertension. Long-term blood pressure management is important after lacunar stroke. Antiplatelet therapy should be instituted for secondary stroke prevention.
Ji Y. Chong, Michael P. Lerario
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Lacunar strokes are strongly associated with hypertension. Long-term blood pressure management is important after lacunar stroke. Antiplatelet therapy should be instituted for secondary stroke prevention.
Ji Y. Chong, Michael P. Lerario
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Small-vessel disease with lacunes.
Advances in neurology, 2003Review
INZITARI, DOMENICO, LAMASSA M.
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1982
The functional significance of “small vessel disease” of the heart receives very different treatment in clinical and pathologic investigations.
G. Rahlf +14 more
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The functional significance of “small vessel disease” of the heart receives very different treatment in clinical and pathologic investigations.
G. Rahlf +14 more
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Vascular Aging and Disease of the Small Vessels
High Blood Pressure & Cardiovascular Prevention, 2019Cardiovascular events are the consequence of vascular damage at both the macro and microcirculatory level. The relationship between large stiffening artery and microvascular disease may be bidirectional, since wave reflection from microvascular sites could increase systolic blood pressure and pulse pressure, while transmission of increased arterial ...
Rizzoni D. +8 more
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Discirculatory encephalopathy and small vessel disease
Zhurnal nevrologii i psikhiatrii im. S.S. Korsakova, 2016The report examines the practicability of the term 'discirculatory encephalopathy' used in the Russian Federation to designate the chronic cerebral ischemia of different origin. The authors discuss the state of small vessel disease which manifests itself through slowly progressive cerebral changes.
Esin R., Esin O., Khairullin I.
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Prevention of Cerebral Small Vessel Disease
Seminars in Neurology, 2017AbstractCerebral small vessel disease can cause either ischemic stroke or intracerebral hemorrhage. Accounting for up to 25% of all strokes, it is also the second biggest contributor to the risk of dementia, and is the most common incidentally discovered finding on brain imaging.
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Hereditary cerebral small vessel diseases: A review
Journal of the Neurological Sciences, 2012Cerebral microangiopathies are responsible of a great number of strokes. In the recent years advances in molecular genetics identified several monogenic conditions involving cerebral small vessels and predisposing to ischemic and/or hemorrhagic stroke and diffuse white matter disease leading to vascular dementia.
FEDERICO, ANTONIO +5 more
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