Results 221 to 230 of about 10,902,324 (285)

TNAP and PHOSPHO1 Function Synergistically to Afford Critical Control Over the Mineralization of the Postnatal Murine Skeleton

Advanced Science, EarlyView.
Biomineralization underpins skeletal development, yet its molecular control remains incompletely understood. Using a novel murine knockout model, this study reveals the essential and complementary roles of PHOSPHO1 and TNAP in postnatal skeletal development.
Lucie E. Bourne, Aikta Sharma, Scott Dillon, Jacob Keen, Soher N. Jayash, Natalie Crump, Lucinda A.E. Evans, Maya Karmali, Worachet Promruk, Claire E. Clarkin, Sonoko Narisawa, Louise Stephen, Brian L. Foster, José Luis Millán, Colin Farquharson, Katherine A. Staines   +15 more
wiley   +1 more source

DTI-ALPS index and cognitive impairment in cerebral small vessel disease: a systematic review and meta-analysis. [PDF]

Front Aging Neurosci
Zeng XX, Xu MX, He X, Huang XL, Yang YY, Mao FL, Qin FL, Wang YQ.   +7 more
europepmc   +1 more source

Structural Basis of Lymphangiogenic Receptor VEGFR‐3 Activation Mediated by Distinctive Clustering of the Ligand–Receptor Complex

Advanced Science, EarlyView.
VEGF‐C and its receptor VEGFR‐3 are critical for lymphangiogenesis. Cryo‐EM structures of the VEGFR‐3/VEGF‐C ectodomain complex reveal a canonical 2:2 ligand–receptor hetero‐tetramer that further assembles into higher‐order clusters beyond simple receptor dimerization.
Ryeongeun Cho, Jinsook Ahn, Jimin Yang, Dong Sun Lee, Gahi Hong, Sangkyu Lee, Ho Min Kim   +6 more
wiley   +1 more source

ASSOCIATION BETWEEN CEREBRAL SMALL VESSEL DISEASE AND ALZHEIMER'S DISEASE PATHOLOGIES

Cerebral Circulation - Cognition and Behavior
Yuan Cai, Wanting Liu, Xiang Fan, Lin Shi, Lisa Wing Chi Au, Bonnie Yin Ka Lam, Jill Abrigo, Vincent Chung Tong Mok   +7 more
doaj   +1 more source

Microstructural Changes in the Corpus Callosum in Different Forms of Sporadic Age-Related Cerebral Small Vessel Disease. [PDF]

Diagnostics (Basel)
Kremneva EI, Dobrynina LA, Shamtieva KV, Geints AA, Sokolov MS, Zabitova MR, Filatov AS, Krotenkova MV.   +7 more
europepmc   +1 more source

Smart Bioinks for 4D Bioprinting: Requirements, Design, and Applications

Advanced Science, EarlyView.
Smart bioinks empower 4D‐bioprinted constructs to dynamically adapt and remodel in response to stimuli, effectively biomimicking native tissues. Artificial Intelligence (AI) and Machine Learning (ML) play a guiding role in their rational design by optimizing relevant properties.
Shangsi Chen, Jiahui Lai, Qiongjiao Zeng, Liangbin Zhou, Boguang Yang, Bin Zhang, Min Wang, Jiajing Zhou, Kieran Lau, Khoon S. Lim, Zhong Alan Li, Rocky S. Tuan   +11 more
wiley   +1 more source

Sex differences in aetiology of intracerebral haemorrhage and associated small vessel disease patterns. [PDF]

Eur Stroke J
Fabisch L, Ozkan H, Nash PS, Zhang W, Locatelli M, Du Y, Panteleienko L, Tamm C, Obergottsberger L, Haidegger M, Kneihsl M, Wünsch G, Enzinger C, Simister RJ, Jäger HR, Gattringer T, Werring DJ, Fandler-Höfler S.   +17 more
europepmc   +1 more source

Adaptive Network Stabilization Despite Profound Structural Reorganization in Human Organotypic Cultures

Advanced Science, EarlyView.
Adult human organotypic cortical slices undergo marked neuronal loss, laminar disruption, and glial activation, yet their network activity progressively stabilizes after a variable period. Electrophysiology, longitudinal calcium imaging, and quantitative histology show that structurally remodeled human circuits show adaptive capacity resulting in ...
Estilla Zsófia Tóth, Rebeka Stelcz, Réka Bod, Ábel Petik, Eszter Juhász, Kinga Tóth, Liza Szalai, Nour Essam, Fanni Somogyi, Beatrix Kovács, Amirmahdi Mojtahedzadeh, Attila György Bagó, Loránd Erőss, Péter Orbay, Johanna Petra Szabó, Dániel Fabó, Boglárka Hajnal, Bence Rácz, Daniel Hillier, István Ulbert, Lucia Wittner   +20 more
wiley   +1 more source

Lacunar stroke with and without chronic imaging biomarkers of small vessel disease: clinical profiles and stroke etiology. [PDF]

Front Neurol
Vynckier J, Jaques L, Maamari B, Goeldlin M, Grunder L, Giannakakis M, Auer E, Sökeland G, Rauch J, Siepen B, Bücke P, Kaesmacher J, Beyeler M, Hakim A, Arnold M, Draganski B, Gralla J, Seiffge DJ, Fischer U, Meinel TR.   +19 more
europepmc   +1 more source