Results 231 to 240 of about 10,358,075 (261)

Photobiomodulation‑Engineered Extracellular Vesicles Enhance Neural Differentiation via UFL1‑Mediated UFMylation in Spinal Cord Injury

Advanced Science, EarlyView.
Photobiomodulated microglia release engineered extracellular vesicles that deliver UFL1 to the injured spinal cord. UFL1 competitively binds p53 with MDM2, inhibiting p53 ubiquitination and stabilizing p53 signaling. This dual mechanism simultaneously promotes anti‐inflammatory microglial polarization and directs neural stem cell differentiation toward
Yunxiao Fang, Zuomeng Wu, Ruocheng Guo, Cancan Wang, Yue Qin, Yixiang Dong, Aoyun Li, Ao Liu, Chongyu Jia, Tianyu Han, Peiwen Song, Lei Chen, Cailiang Shen   +12 more
wiley   +1 more source

The role of dopamine decline, astrocyte reactivity and cerebral small-vessel disease in cognitive aging. [PDF]

J Cereb Blood Flow Metab
Crine V, Johansson J, Ericsson O, Wåhlin A, Axelsson J, Anderssson M, Nyberg L, Karalija N.   +7 more
europepmc   +1 more source

Serial Molecular‐Microstructural Multimodal Intravascular Imaging of Atherosclerotic Plaques in Mice

Advanced Science, EarlyView.
A novel longitudinal molecular and microstructural intravascular imaging approach is developed to study murine atherosclerosis. The technique combines a unique surgical model with a miniaturized multimodal device to detect macrophage activity and lipid simultaneously.
Jiawen Li, Joanne T. M. Tan, Lei Xiang, Jiandi Liu, Ayla Hoogendoorn, Victoria A. Nankivell, Lauren Sandeman, Richard Le, Rouyan Chen, Robert A. McLaughlin, Peter J. Psaltis, Johan W. Verjans, Christina A. Bursill   +12 more
wiley   +1 more source

Stroke, Small-Vessel Disease, and Occupation: Systematic Review and Data Analysis. [PDF]

J Am Heart Assoc
Zhang T, Clancy U, Singh A, Makin S, McHutchison C, Cvoro V, Arteaga-Reyes C, Garcia DJ, Hewins W, Stringer M, Thrippleton M, Valdes-Hernandez MC, Wiseman S, Chappell F, Brown R, Doubal F, Wardlaw JM.   +16 more
europepmc   +1 more source

Plasma Proteomic Signatures of Left Atrial Dysfunction and Cerebral Small Vessel Disease: Elucidating Heart-Brain Connections. [PDF]

JACC Basic Transl Sci
Tan ESJ, Sim MA, Choi H, Chan SP, Cai VY, Gong L, Venketasubramanian N, Tan BY, Hilal S, Lai MKP, Ling LH, Richards AM, Chen C.   +12 more
europepmc   +1 more source

Biomarker-based assessment of cerebral small vessel disease progression after ischemic stroke - a prospective cohort study (MA-BIO). [PDF]

Neurol Res Pract
Hasanova L, Klassen P, Nosanova A, Babayeva M, Lulé D, Tumani H, Müller HP, Yilmazer-Hanke D, Sollmann N, Kreiser K, Haeusler KG, Laible M.   +11 more
europepmc   +1 more source

Abrupt Pericyte Loss Precedes Endothelial Activation in Cerebral Small Vessel Disease

Chagnot A, Jaime Garcia D, McQuaid C, Cholewa-Waclaw J, McDade K, Dando O, Wardlaw J, Smith C, Montagne A.   +8 more
europepmc   +1 more source