Results 21 to 30 of about 1,168,068 (349)

Mechanisms of sporadic cerebral small vessel disease: insights from neuroimaging

Lancet Neurology, The, 2013
Joanna M Wardlaw, Colin Smith, Martin Dichgans   +2 more
exaly   +2 more sources

Association of inflammatory markers with cerebral small vessel disease in community-based population

Journal of Neuroinflammation, 2022
This study investigated the relationships of neutrophil count (NC), neutrophil-to-lymphocyte ratio (NLR) and systemic immune-inflammation index (SII) with cerebral small vessel disease (CSVD).
Li-Na Jiang, Xueli Cai, Dong-xiao Yao, J. Jing, Lerong Mei, Yingying Yang, Shan Li, A. Jin, Xia Meng, Hao Li, Tiemin Wei, Yongjun Wang, Yuesong Pan, Yilong Wang   +13 more
semanticscholar   +1 more source

Effect of Long-term Continuous Cardiac Monitoring vs Usual Care on Detection of Atrial Fibrillation in Patients With Stroke Attributed to Large- or Small-Vessel Disease: The STROKE-AF Randomized Clinical Trial.

Journal of the American Medical Association (JAMA), 2021
Importance Patients with ischemic stroke attributed to large- or small-vessel disease are not considered at high risk for atrial fibrillation (AF), and the AF incidence rate in this population is unknown.
R. Bernstein, H. Kamel, C. Granger, J. Piccini, Pramod Sethi, J. Katz, Carola Alfaro Vives, P. Ziegler, Noreli Franco, L. Schwamm   +9 more
semanticscholar   +1 more source

Cerebral small vessel disease: Pathological mechanisms and potential therapeutic targets

Frontiers in Aging Neuroscience, 2022
Cerebral small vessel disease (CSVD) represents a diverse cluster of cerebrovascular diseases primarily affecting small arteries, capillaries, arterioles and venules.
Yue Gao, Di Li, Jianwen Lin, Aline M. Thomas, Jianyu Miao, Dong Chen, Shen Li, Chengyan Chu   +7 more
semanticscholar   +1 more source

HTRA1-related autosomal dominant cerebral small vessel disease

Chinese Medical Journal, 2021
. Background. Homozygous or compound heterozygous mutations in high temperature requirement serine peptidase A1 (HTRA1) gene are responsible for cerebral autosomal recessive arteriopathy with subcortical infarcts and leukoencephalopathy (CARASIL ...
Jing-Yi Liu, Yi-Cheng Zhu, Li-Xin Zhou, Yan-Ping Wei, Chen-Hui Mao, Li-Ying Cui, Bin Peng, Ming Yao, Xin Chen   +8 more
doaj   +1 more source

Advanced MRI in cerebral small vessel disease

International Journal of Stroke, 2022
Cerebral small vessel disease (cSVD) is a major cause of stroke and dementia. This review summarizes recent developments in advanced neuroimaging of cSVD with a focus on clinical and research applications.
H. van den Brink, F. Doubal, Marco Duering   +2 more
semanticscholar   +1 more source

Cerebral small vessel disease and vascular cognitive impairment: from diagnosis to management

Current Opinion in Neurology, 2021
Purpose of review We present recent developments in the field of small vessel disease (SVD)-related vascular cognitive impairment, including pathological mechanisms, updated diagnostic criteria, cognitive profile, neuroimaging markers and risk factors ...
M.C. Zanon Zotin, L. Sveikata, A. Viswanathan, P. Yilmaz   +3 more
semanticscholar   +1 more source

Framework for Clinical Trials in Cerebral Small Vessel Disease (FINESSE): A Review.

JAMA Neurology, 2022
Importance Cerebral small vessel disease (SVD) causes a quarter of strokes and is the most common pathology underlying vascular cognitive impairment and dementia. An important step to developing new treatments is better trial methodology.
H. Markus, W. M. van der Flier, E. Smith, P. Bath, G. Biessels, E. Briceño, Amy Brodtman, H. Chabriat, Christopher P L H Chen, F. de Leeuw, M. Egle, A. Ganesh, Marios K. Georgakis, R. Gottesman, S. Kwon, L. Launer, Vincent C. T. Mok, J. O'Brien, Lois Ottenhoff, S. Pendlebury, E. Richard, P. Sachdev, R. Schmidt, Melanie Springer, Stefan Tiedt, J. Wardlaw, A. Verdelho, A. Webb, D. Werring, Marco Duering, D. Levine, M. Dichgans   +31 more
semanticscholar   +1 more source

CNS small vessel disease [PDF]

Neurology, 2019
CNS small vessel disease (CSVD) causes 25% of strokes and contributes to 45% of dementia cases. Prevalence increases with age, affecting about 5% of people aged 50 years to almost 100% of people older than 90 years. Known causes and risk factors include age, hypertension, branch atheromatous disease, cerebral amyloid angiopathy, radiation exposure ...
Rocco J. Cannistraro, Mohammed Badi, Benjamin H. Eidelman, Dennis W. Dickson, Erik H. Middlebrooks, James F. Meschia   +5 more
openaire   +2 more sources

Inflammatory biomarkers and cerebral small vessel disease: a community-based cohort study

Stroke and vascular neurology, 2022
Background and purpose Although inflammation has been proposed to be a candidate risk factor for cerebral small vessel disease (CSVD), previous findings remain largely inconclusive and vary according to disease status and study designs. The present study
Dingding Zhang, Yuan Cao, Jingwei Mu, Yiming Liu, F. Gao, F. Han, F. Zhai, Li-xin Zhou, J. Ni, M. Yao, Ming-Li Li, Zheng-Yu Jin, Shu-yang Zhang, L. Cui, Yong Shen, Yicheng Zhu   +15 more
semanticscholar   +1 more source