Results 91 to 100 of about 63,544 (259)
Navigating resistance in global health governance: Certification of smallpox eradication in China
Global Public HealthCertification is an essential stage in disease eradication efforts, encompassing epidemiological, managerial, and political complexities. The certification of smallpox eradication in the People’s Republic of China (PRC, or China) exemplifies the ...
Lu Chen
doaj +1 more source
Dynamic Cap‐Mediated Substrate Access and Potent Inhibitor Design of Monkeypox Virus I7L Protease
Advanced Science, Volume 12, Issue 26, July 10, 2025.The first crystal structure of MPXV I7L protease, revealing its unique dimeric form is resolved. The structures and MD simulations uncovered a dynamic cap region that regulates substrate access to the active site. The structural basis of substrate recognition and the catalytic mechanism are elucidated, which led to the development of a FRET‐based assay
Haixia Su +12 more
wiley +1 more source
BMC Public Health, 2004 Background Previous smallpox ring vaccination models based on contact tracing over a network suggest that ring vaccination would be effective, but have not explicitly included response logistics and limited numbers of vaccinators.
Portnoy Diane L +5 more
doaj +1 more source
Japanese journal of infectious diseases (Print), 2017 Monkeypox virus (MPXV) causes human monkeypox (human MPX), which is a similar disease to smallpox in humans. A previous study showed that a single vaccination of monkeys with LC16m8, a highly attenuated smallpox vaccine, protected them from MPX from 4-5 ...
Itoe Iizuka +10 more
semanticscholar +1 more source
Advanced NanoBiomed Research, Volume 5, Issue 7, July 2025.Chemically modified graphene oxide nanocarriers provide a targeted lung cancer gene therapy platform. In a 3D tumor microenvironment model, these nanocarriers deliver therapeutic genes, regulate immune markers, and induce apoptosis in cancer cells. Combined gene delivery enhances cancer cell elimination, demonstrating the potential of this approach for
Francesca Grilli +3 more
wiley +1 more source
Developing New Smallpox Vaccines
Emerging Infectious Diseases, 2001 New stockpiles of smallpox vaccine are required as a contingency for protecting civilian and military personnel against deliberate dissemination of smallpox virus by terrorists or unfriendly governments.
Steven R. Rosenthal +3 more
doaj +1 more source
Defending against smallpox: a focus on vaccines
Expert Review of Vaccines, 2016 Smallpox has shaped human history, from the earliest human civilizations well into the 20th century. With high mortality rates, rapid transmission, and serious long-term effects on survivors, smallpox was a much-feared disease.
E. Voigt, R. Kennedy, G. Poland
semanticscholar +1 more source
JAMA: The Journal of the American Medical Association, 1902 During epidemics of smallpox the anticipatory attitude of the physician's mind will often lead him to suspect as variola diseases which bear only a superficial resemblance to it. Contrariwise, in the absence of epidemic prevalence of smallpox, mild cases are apt to be overlooked.
openaire +2 more sources
No Smallpox in Minnesota. [PDF]
JAMA: The Journal of the American Medical Association, 1894 Red Wing, Minn., March 6, 1894. To the Editor: Please contradict the report of smallpox in St. Paul. There has been none there this year. The report of students exposed therefore is a mistake. There is none in Minnesota.
openaire +3 more sources
Characterization of Two Historic Smallpox Specimens from a Czech Museum
Viruses, 2017 Although smallpox has been known for centuries, the oldest available variola virus strains were isolated in the early 1940s. At that time, large regions of the world were already smallpox-free.
P. Pajer +22 more
semanticscholar +1 more source