Results 61 to 70 of about 103,751 (236)

Analysis of aerobiological studies with orthopoxviruses by U.S. Department of Defense

open access: yesЖурнал микробиологии, эпидемиологии и иммунобиологии
Discontinuation of vaccination after the completion of Smallpox global eradication program led to a sharp decrease in the level of collective immunity not only to smallpox but also to other orthopoxvirus infections.
Gennady G. Onishenko   +4 more
doaj   +1 more source

Should Remaining Stockpiles of Smallpox Virus (Variola) Be Destroyed?

open access: yesEmerging Infectious Diseases, 2011
In 2011, the World Health Organization will recommend the fate of existing smallpox stockpiles, but circumstances have changed since the complete destruction of these cultures was first proposed.
Raymond S. Weinstein
doaj   +1 more source

Assessing Risk Thresholds in Controlled Human Infection Models (CHIM)

open access: yesBioethics, EarlyView.
ABSTRACT Controlled Human Infection Models (CHIMs) are a type of clinical trial involving deliberately exposing human volunteers to an infectious agent. Compared to studies of natural infection, CHIMs offers distinctive benefits, from the ability to study presymptomatic infection to a direct assessment of the efficacy of vaccines and therapeutics in a ...
Alexa Nord‐Bronzyk   +4 more
wiley   +1 more source

A vaccinia virus renaissanceNew vaccine and immunotherapeutic uses after smallpox eradication

open access: yesHuman Vaccines & Immunotherapeutics, 2012
In 1796, Edward Jenner introduced the concept of vaccination with cowpox virus, an Orthopoxvirus within the family Poxviridae that elicits cross protective immunity against related orthopoxviruses, including smallpox virus (variola virus).
Paulo H. Verardi   +2 more
doaj   +1 more source

Misinformation and women's health: Rebuilding trust in evidence‐based care

open access: yes
International Journal of Gynecology &Obstetrics, EarlyView.
Zainab Al‐Jawahiri
wiley   +1 more source

Oncolytic Vaccinia Virus‐HSP70‐shRNA Amplifies Viral Replication, ROS/Autophagy, and Immunity to Fight Colorectal Cancer

open access: yesCancer Science, EarlyView.
OncoVV‑shHSP70, a vaccinia virus silencing HSP70, demonstrated potent antitumor efficacy in colorectal cancer cell lines, as well as in syngeneic, xenograft, and humanized mouse models. In cell lines, oncoVV‑shHSP70 promoted viral oncolysis and cytokine production through a self‑reinforcing cycle of ROS‑autophagy. In both CT26 and SW620‑humanized mouse
Rentao Yuan   +8 more
wiley   +1 more source

Smallpox and New York City’s Smallpox Hospital [PDF]

open access: yesJournal of Community Health, 2005
Threatened use of the smallpox virus in bioterrorist attacks recently prompted national concerns in the United States. Smallpox, the "speckled monster," was known in antiquity. In 1856, New York City opened its first hospital devoted to caring for victims of smallpox.
Spiegel, Allen D.   +2 more
openaire   +2 more sources

Sick leave in the United Kingdom Post Office, 1850–1908

open access: yesThe Economic History Review, EarlyView.
Abstract This paper uses a large individual‐record‐level dataset on sick leave to examine adult morbidity in the United Kingdom between 1850 and 1908. From 1859 onwards postal workers were eligible to receive a pension or gratuity when they retired or were forced to stop working due to ill health.
Harry Smith   +8 more
wiley   +1 more source

Evidence of Long-Distance Aerial Convection of Variola Virus and Implications for Disease Control

open access: yesViruses, 2019
Two distinct phenomena of airborne transmission of variola virus (smallpox) were described in the pre-eradication era—direct respiratory transmission, and a unique phenomenon of transmission over greater distances, referred to as “aerial ...
Chandini Raina MacIntyre   +4 more
doaj   +1 more source

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