Mechanistic Exploration of Smilax glabra Roxb. in Osteoarthritis: Insights from Network Pharmacology, Molecular Docking, and In Vitro Validation [PDF]
PharmaceuticalsBackground: Arthritis, a debilitating joint disease, remains a significant global health burden. This study uncovers the therapeutic potential of the medicinal plant Smilax glabra Roxb.
Sidra Ilyas +5 more
doaj +2 more sources
PHYTOCHEMICAL ANALYSIS OF SOME MEDICINAL PLANTS [PDF]
Liaquat Medical Research Journal, 2021 The chemical compounds that formed in plants during the normal metabolic process are termed as phytochemicals. The composition of phytochemicals is usually complex in nature and differs among stages of development and plant origin.
MAHAM SIDDIQUI +5 more
doaj +1 more source
Polysaccharide from Smilax glabra Roxb Mitigates Intestinal Mucosal Damage by Therapeutically Restoring the Interactions between Gut Microbiota and Innate Immune Functions. [PDF]
Nutrients, 2023 Smilax glabra Roxb (S. glabra) is a conventional Chinese medicine that is mainly used for the reliability of inflammation. However, bioactive polysaccharides from S. glabra (SGPs) have not been thoroughly investigated.
Abaidullah M +8 more
europepmc +2 more sources
Molecules, 2015 Astilbin, a dihydroflavonol derivative found in many food and medicine plants, exhibited multiple pharmacological functions. In the present study, the ethanol extraction of astilbin from the rhizome of smilax glabra Roxb was optimized by response surface
Chuan-Li Lu, Meng-Mei Hu
exaly +3 more sources
Astilbin Inhibits RANKL-Induced Osteoclasts by Suppressing PI3K/Akt Signaling Pathway
Journal of ChemistryThis study evaluated the in vitro and in vivo antiresorptive effects of astilbin, isolated from Smilax glabra Roxb roots, on RANKL-induced osteoclastogenesis using RAW 264.7 cell culture and a transgenic medaka (Oryzias latipes) fish model of ...
Huyen T. T. Nguyen +7 more
doaj +2 more sources
The American Journal of Chinese Medicine, 2018 Smilax glabra (SG) Roxb., a well-known traditional Chinese medicine, has been extensively used worldwide for its marked pharmacological activities for treating syphilitic poisoned sores, limb hypertonicity, morbid leucorrhea, eczema pruritus, strangury due to heat, carbuncle toxin, and many other human ailments.
Shiyao, Hua +6 more
openaire +3 more sources
An ethnobotanical study of the genus Smilax in Thailand and its botanical authentication for Hua-khao-yen crude drugs [PDF]
Pharmaceutical Sciences Asia, 2022 The first ethnobotanical work of the genus Smilax in Thailand was carried out to investigate the medicinal use of the Smilax species by folk healers, using the semi-structured interview, questionnaire survey, and literature review.
Pithkanda Pansumrit +5 more
doaj +1 more source
, 2019 Ozark National Forest, Norfork, AR, UShttps://orc.library.atu.edu/smilax/1015/thumbnail ...
Chapman, Creed
core +12 more sources
Two new species of Diaporthe (Diaporthaceae, Diaporthales) in China [PDF]
MycoKeys, 2023 Species of Diaporthe have been reported as plant endophytes, pathogens and saprobes on a wide range of plant hosts. Strains of Diaporthe were isolated from leaf spots of Smilax glabra and dead culms of Xanthium strumarium in China, and identified based ...
Ya-Quan Zhu +5 more
doaj +3 more sources
Explore the Mechanism of Xiaoyaosan for Treatment of Bipolar Disorder Based on Network Pharmacology, Experimental Validation and Molecular Docking. [PDF]
CNS Neurosci TherThis study evaluates Xiaoyaosan (XYS) for bipolar disorder (BD) using network pharmacology and experimental validation. Molecular docking reveals interactions between active XYS compounds and potential core targets. Animal experiments confirm XYS alleviates BD‐like behaviors in mice by suppressing core targets, elucidating its multi‐target mechanism ...
Chen M +10 more
europepmc +2 more sources