치위생과학회지, 2023 Background: Smilax glabra has various pharmacological activities and is widely used as a herbal medicine. Although the incidence of oral cancer is low, the recurrence rate is high, and the 5-year survival rate is poor.
Young Sun Hwang
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<i>Smilax glabra</i> Flavonoids Inhibit AMPK Activation and Induce Ferroptosis in Obesity-Associated Colorectal Cancer. [PDF]
Int J Mol SciSmilax glabra flavonoids (SGF), the active components of Smilax glabra Roxb., have been demonstrated to exhibit antioxidant activity and metabolic benefits in obesity, leading us to further explore their antitumor effects in obesity-related colorectal cancer (CRC).
Xu J +6 more
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Smilax glabra flavonoids ameliorate non-alcoholic steatohepatitis by regulating PKM2-dependent glycolysis and suppressing AIM2 inflammasome activation [PDF]
Frontiers in ImmunologyBackgroundNonalcoholic steatohepatitis (NASH) is a prevalent chronic liver disease characterized by hepatic steatosis, persistent inflammation and progressive liver damage. Smilax glabra flavonoids (SGF), the major bioactive constituents of Smilax glabra
Ziyao Pang +8 more
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Antioxidant and Anti-Inflammatory Activities of Phenolic-Enriched Extracts of Smilax glabra. [PDF]
Evid Based Complement Alternat Med, 2014 Smilax glabra Roxb. has been used for a long time as both food and folk medicine. In the present study, phenolic‐enriched extract of S. glabra (PEESG) was extracted with 70% ethanol and purified by HP‐20 column chromatography. Its antioxidant and anti‐inflammatory activities were evaluated by radical scavenging assay, reducing power determination, and ...
Lu CL, Zhu W, Wang M, Xu XJ, Lu CJ.
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Flavonoid Group of Smilax glabra Roxb. Regulates the Anti-Tumor Immune Response Through the STAT3/HIF-1 Signaling Pathway [PDF]
Frontiers in Pharmacology, 2022 Background:Smilax glabra Roxb. (SGR) is a widely used traditional Chinese medicine, which has known effects of enhancing immunity. However, its anti-tumor effects and mechanism of action are still unclear.Methods: We selected MMTV-PyMT mice to determine ...
Yingxue Guo +16 more
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Protective Effects of Smilax glabra Roxb. Against Lead-Induced Renal Oxidative Stress, Inflammation and Apoptosis in Weaning Rats and HEK-293 Cells [PDF]
Frontiers in Pharmacology, 2020 Lead (Pb) is an important environmental pollutant. Oxidative stress and the inflammatory response have been postulated as mechanisms involved in lead-induced renal damage. Smilax glabra Roxb.
Yueyue Shi +7 more
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Hypoglycemic activity of the ethyl acetate extract from Smilax glabra Roxb in mice: Biochemical and histopathological studies [PDF]
Iranian Journal of Basic Medical Sciences, 2020 Objective(s): This research was carried out to investigate the hypoglycemic activity of the ethyl acetate (EtOAc) extract from the roots of Smilax glabra Roxb, which strongly exhibit inhibitory activity against α-glucosidase and α-amylase on in vivo type
Phuong Nguyen +4 more
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Component characterization of Smilax glabra Roxb., and its inhibitory activity against Helicobacter pylori through targeted suppression of its secreted urease [PDF]
Frontiers in Cellular and Infection MicrobiologyBackgroundSmilax glabra Roxb. (SGR), known as “tufuling” in China, is a medical and edible plant, which has anti-inflammatory, antibacterial and antineoplastic activity. SGR is extensively utilized in the remedy of gastroenteric disorders associated with
Ying Tang +9 more
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Smilax glabra Roxb. Inhibits Collagen Induced Adhesion and Migration of PC3 and LNCaP Prostate Cancer Cells through the Inhibition of Beta 1 Integrin Expression [PDF]
Molecules, 2020 Smilax glabra Roxb. (SGR) has been used as a traditional medicine for brucellosis and syphilis. In this study, we investigated whether nontoxicological levels of water extract of SGR (WESGR) are effective for suppressing steps in the progression of ...
Oh Yun Kwon +3 more
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Multidimensional therapeutic advantages of Smilax glabra (Tufuling)-containing formulae in gout: an integrated Systematic Review and network pharmacology-based prediction [PDF]
Frontiers in EndocrinologyBackgroundGout, an inflammatory form of arthritis triggered by monosodium urate (MSU) crystal deposition, poses a substantial global health burden with increasing prevalence and younger onset, particularly in China. In traditional Chinese medicine (TCM),
Qiaoyun Liu +15 more
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