Results 11 to 20 of about 22,074 (160)

Mechanistic Exploration of Smilax glabra Roxb. in Osteoarthritis: Insights from Network Pharmacology, Molecular Docking, and In Vitro Validation [PDF]

Pharmaceuticals
Background: Arthritis, a debilitating joint disease, remains a significant global health burden. This study uncovers the therapeutic potential of the medicinal plant Smilax glabra Roxb.
Sidra Ilyas, Chae Yun Baek, Abdul Manan, Yeojin Choi, Hee-Geun Jo, Donghun Lee   +5 more
doaj   +5 more sources

Smilax glabra Roxb. Inhibits Collagen Induced Adhesion and Migration of PC3 and LNCaP Prostate Cancer Cells through the Inhibition of Beta 1 Integrin Expression [PDF]

Molecules, 2020
Smilax glabra Roxb. (SGR) has been used as a traditional medicine for brucellosis and syphilis. In this study, we investigated whether nontoxicological levels of water extract of SGR (WESGR) are effective for suppressing steps in the progression of ...
Oh Yun Kwon, Sujin Ryu, Jong Kyu Choi, Seung Ho Lee   +3 more
doaj   +3 more sources

Smilax glabra Roxb.: A Review of Its Traditional Usages, Phytochemical Constituents, Pharmacological Properties, and Clinical Applications

Drug Design, Development and Therapy, 2022
Hao Wu,1,* Yu Wang,1,* Bing Zhang,1,2 Yao-lei Li,1 Zhi-xin Ren,1 Jing-jian Huang,1 Zhi-qi Zhang,1 Zhi-jian Lin,1 Xiao-meng Zhang1 1Department of Clinical Chinese Pharmacy, School of Chinese Materia Medica, Beijing University of Chinese Medicine ...
Bing Zhang, Zhi-Qi Zhang
exaly   +3 more sources

Polysaccharide from Smilax glabra Roxb Mitigates Intestinal Mucosal Damage by Therapeutically Restoring the Interactions between Gut Microbiota and Innate Immune Functions. [PDF]

Nutrients, 2023
Smilax glabra Roxb (S. glabra) is a conventional Chinese medicine that is mainly used for the reliability of inflammation. However, bioactive polysaccharides from S. glabra (SGPs) have not been thoroughly investigated. Here, we demonstrate for the first time that SGPs preserve the integrity of the gut epithelial layer and protect against intestinal ...
Abaidullah M, La S, Liu M, Liu B, Cui Y, Wang Z, Sun H, Ma S, Shi Y.   +8 more
europepmc   +4 more sources

Mitochondrial apoptosis contributes to the anti-cancer effect of Smilax glabra Roxb.

Toxicology Letters, 2011
Smilax glabra Roxb. (SGR), a member of the Smilacaceae family and a rhizome of the Liliaceae plant, has shown anti-inflammation and detoxification properties, and a few studies reported its anti-cancer effect. In this study, we showed that SGR inhibited growth of human breast cancer cell line MCF7, colon carcinoma cell line HT-29, and gastric cancer ...
Yujing, Gao, Yahui, Su, Like, Qu, Shuo, Xu, Lin, Meng, Shao-Qing, Cai, Chengchao, Shou   +6 more
openaire   +3 more sources

Predicting future habitat suitability of Smilax glabra under climate change scenarios [PDF]

Scientific Reports
The rhizome of Smilax glabra Roxb., known as Smilacis glabrae Rhizoma, is extensively used in Traditional Chinese Medicine for relieving dampness and other health issues. The growth patterns and geographical distribution of S.
Xu Sun, Junjie Guan, Ling Meng, Chun Wang, Na Chen, Tao Wei, Shihai Xing   +6 more
doaj   +2 more sources

The herbal pair of Smilax glabra Roxb. and Ficus hirta Vahl. improves exercise performance by regulating mitochondrial function via the adiponection receptors-mediated AMPK signaling pathway [PDF]

Frontiers in Nutrition
IntroductionExercise fatigue can significantly impair physical function, while herbal medicines exhibit broad application prospects in anti-fatigue research. The herbal pair of Smilax glabra Roxb. and Ficus hirta Vahl.
Ya-Nan Bao, Wen-Hao Wang, Hai-Xia Yang, Lei Qian, Xue Sui, Meng Wang, Bo-Wei Su, Fang-Yuan Chen, Xiao-Hui Cui, Xiao-Hui Cui, Jia-Yi Lao, Rui-Kang Wen, Hong-Yu Ji, Wen-Juan Hu, Lin Wen, Hui-Wen Ren, Zhi-Lin Luan, Zhi-Lin Luan   +17 more
doaj   +2 more sources

Astilbin Inhibits RANKL-Induced Osteoclasts by Suppressing PI3K/Akt Signaling Pathway

Journal of Chemistry
This study evaluated the in vitro and in vivo antiresorptive effects of astilbin, isolated from Smilax glabra Roxb roots, on RANKL-induced osteoclastogenesis using RAW 264.7 cell culture and a transgenic medaka (Oryzias latipes) fish model of ...
Huyen T. T. Nguyen, Thuy Thanh To, Bao Quoc Nguyen, Dang Hai Nguyen, Huong Thanh Le, Nhung Thi Duong, Anh Tuong Nguyen, Phuong T. M. Nguyen   +7 more
doaj   +2 more sources

Flavonoid biosynthesis in Smilax glabra Roxb: Insights from integrated transcriptomic and metabolomic approach

Industrial Crops and Products
Smilax glabra Roxb. (S. glabra) is a traditional Chinese medicinal plant, and the rhizome of S. glabra (SGR) serves as a key ingredient in numerous herbal formulations.
Guojian Liao, Wenjing Liang, Yan Qin, Haixia Yu, Linxuan Li, Shixin Feng, Lisha Song, Cuihong Yang, Zhanjiang Zhang, Dongqiang Zeng, Shugen Wei   +10 more
doaj   +2 more sources

Engeletin Targets Mitochondrial Dysfunction to Attenuate Oxidative Stress and Experimental Colitis in Intestinal Epithelial Cells Through AMPK/SIRT1/PGC-1α Signaling [PDF]

Antioxidants
Inflammatory bowel disease (IBD), encompassing Crohn’s disease and ulcerative colitis, is characterized by chronic intestinal inflammation and epithelial barrier disruption.
Jing Li, Zhijun Geng, Lixia Yin, Ju Huang, Minzhu Niu, Keni Zhang, Xue Song, Yueyue Wang, Lugen Zuo, Jianguo Hu   +9 more
doaj   +2 more sources