Results 91 to 100 of about 2,634,989 (242)

LLM‐Based Scientific Assistants for Knowledge Extraction: Which Design Choices Matter?

Advanced Intelligent Discovery, EarlyView.
A comprehensive framework for optimizing Large Language Models in domain‐specific applications is introduced. The LLM Playground integrates Prompt Engineering, knowledge augmentation, and advanced reasoning strategies to enable systematic comparison of architectures and base models.
David Exler, Manuel Raimann, Marc Münker, Maxim Rosin, Joaquin E. Urrutia Gómez, Christof M. Niemeyer, Markus Reischl, Luca Rettenberger   +7 more
wiley   +1 more source

Toward Predictable Nanomedicine: Current Forecasting Frameworks for Nanoparticle–Biology Interactions

Advanced Intelligent Discovery, EarlyView.
Predictive models successfully screen nanoparticles for toxicity and cellular uptake. Yet, complex biological dynamics and sparse, nonstandardized data limit their accuracy. The field urgently needs integrated artificial intelligence/machine learning, systems biology, and open‐access data protocols to bridge the gap between materials science and safe ...
Mariya L. Ivanova, Michael Nicholls, Nicola Russo, Gueorgui Mihaylov, Konstantin Nikolic   +4 more
wiley   +1 more source

When Biology Meets Medicine: A Perspective on Foundation Models

Advanced Intelligent Discovery, EarlyView.
Artificial intelligence, and foundation models in particular, are transforming life sciences and medicine. This perspective reviews biological and medical foundation models across scales, highlighting key challenges in data availability, model evaluation, and architectural design.
Kunying Niu, Yuxing Wang, Limin Zou, Jing Huang   +3 more
wiley   +1 more source

Smile analysis following orthognathic surgery

is study compared the different views between orthodontists and oral maxillofacial surgeons, as for smile analysis in patients subjected to orthognathic surgery.
Gabriel Ramalho Ferreira, Leonardo Perez Faverani, Gustavo Augusto Grossi de Oliveira, André Luis da Silva Fabris, Cláudio Maldonado Pastori, Omar Gabriel da Silva Filho
core  

Why do we smile? On the determinants of the implied volatility function. [PDF]

We report simple regressions and Granger causality tests in order to understand the pattern of implied volatilities across exercise prices. We employ all calls and puts transacted between 16:00 and 16:45 on the Spanish IBEX-35 index from January 1994 to ...
Rubio, Gonzalo, Peña Sánchez de Rivera, Juan Ignacio, Serna, Gregorio   +2 more
core  

Cardioprotective role of zofenopril in hypertensive patients with acute myocardial infarction: a pooled individual data analysis of the SMILE studies

, 2017
Purpose: The four SMILE studies demonstrated that early administration of zofenopril following acute myocardial infarction is prognostically beneficial compared to placebo or other angiotensin-converting enzyme (ACE) inhibitors.
Omboni, Stefano, BACCHELLI, STEFANO, AMBROSIONI, ETTORE, : on behalf of the SMILE Working Project, Null, DEGLI ESPOSTI, DANIELA, Reggiardo, Giorgio, BORGHI, CLAUDIO   +6 more
core   +1 more source

Multi‐Property Machine Learning Models to Accelerate the Transition Toward Bio‐Based Emulsion Polymers

Advanced Intelligent Discovery, EarlyView.
A machine learning framework simultaneously predicts four critical properties of monomers for emulsion polymerization: propagation rate constant, reactivity ratios, glass transition temperature, and water solubility. These tools can be used to systematically identify viable bio‐based monomer pairs as replacements for conventional formulations, with ...
Kiarash Farajzadehahary, Nicholas Ballard   +1 more
wiley   +1 more source

Trueness, precision, and internal fit of additively and subtractively manufactured definitive resin-based crowns.

Journal of Prosthodontics
PURPOSE To assess the fabrication trueness, precision, and internal fit of additively manufactured (AM) and subtractively manufactured (SM) resin-based definitive crowns.
Ahmet Orgev, Rui Li, B. Yılmaz, Gülçe Çakmak   +3 more
semanticscholar   +1 more source

Стимулювання інновацій та підприємництва в розумному виробництві. Аналітична записка. [PDF]

Ця аналітична записка була підготовлена в рамках проєкту SMILE (Інновації, навчальні лабораторії та підприємництво у сфері розумного виробництва) Європейського інституту інновацій і технологій в програмі “Horizon Europe” і призначена для освітніх ...
консорціум SMILE EIT HEI Innovate
core   +1 more source

Large‐Scale Machine Learning to Screen for Small‐Molecule Senolytics

Advanced Intelligent Discovery, EarlyView.
A consistent workflow underpins all experiments in this study. A dedicated model‐selection dataset first identifies optimal hyperparameters for each algorithm. Models are then trained and rigorously evaluated on independent sets of molecules using the senolytic ratio SR. Comprehensive hyperparameter exploration across SMILES representations, task types,
Alexis Dougha, Jesus Gil, Pedro J. Ballester   +2 more
wiley   +1 more source